Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

72 questions · 72 findings · 13 reviews

No studies found 19 · 26.4%GRADE not reported 2 · 2.8%Very low 20 · 27.8%Low 27 · 37.5%Moderate 4 · 5.6%High 0 · 0%

Agomelatine vs placebo

Adverse events as N of participants with at least one adverse event subjective and objective · adults with a history of SAD

It is very uncertain whether agomelatine changes number of persons with at least one adverse event within a year compared with placebo (very low certainty).

1 finding from 1 review

Agomelatine vs placebo

Number of participants experiencing at least one severe adverse event · adults with a history of SAD

It is very uncertain whether agomelatine changes number of persons with at least one severe adverse event within a year compared with placebo (very low certainty).

1 finding from 1 review

Intervention not reported

Quantity and quality of sleep as measured through reports of participants or of family members or by personnel assessments Data collected at end of · adult patients in the ICU
1 finding from 1 review