Findings

What do systematic reviews say?

67 questions · 67 findings · 6 reviews · Urology

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No studies found 18 · 26.9%GRADE not reported 0 · 0%Very low 17 · 25.4%Low 22 · 32.8%Moderate 9 · 13.4%High 1 · 1.5%

Alpha‐blockers vs usual care

Hospital admissions · adult patients presenting with symptoms of ureteral stone disease

Alpha‐blockers probably leads to lower hospitalisation compared with standard therapy (moderate certainty).

1 finding from 1 review

Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
RR 0.51 [0.34, 0.77]
13 studies · 1876 participants
Moderate

Alpha‐blockers vs usual care

Surgical intervention · adult patients presenting with symptoms of ureteral stone disease

Alpha‐blockers showed no clear difference in surgical intervention compared with standard therapy (low certainty).

1 finding from 1 review

Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
RR 0.74 [0.53, 1.02]
19 studies · 3292 participants
Low

Alpha‐blockers vs placebo

Stone clearance · adult patients presenting with symptoms of ureteral stone disease

Alpha‐blockers probably leads to higher stone clearance compared with placebo (moderate certainty).

1 finding from 1 review

Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
RR 1.16 [1.07, 1.25]
15 studies · 5787 participants
Moderate

Alpha‐blockers vs placebo

Major adverse events · adult patients presenting with symptoms of ureteral stone disease

Alpha‐blockers probably leads to higher major adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
RR 2.09 [1.13, 3.86]
10 studies · 1650 participants
Moderate

Potassium citrate vs no intervention

Proportion of participants who developed a new urinary stone · children with idiopathic urinary calculi treated with shockwave lithotripsy

Potassium citrate may leads to lower proportion of participants who developed a new urinary stone compared with no intervention (low certainty).

1 finding from 1 review

Medical and dietary interventions for preventing recurrent urinary stones in children 2017 · Cochrane Headline outcomes only
RR 0.19 [0.06, 0.6]
1 study · 96 participants
Low

Potassium citrate vs no intervention

Proportion of participants with adverse events while undergoing intervention · children with idiopathic urinary calculi treated with shockwave lithotripsy

It is very uncertain whether potassium citrate changes proportion of participants with adverse events while undergoing… compared with no intervention (very low certainty).

1 finding from 1 review

Medical and dietary interventions for preventing recurrent urinary stones in children 2017 · Cochrane Headline outcomes only
RR 13 [0.75, 224.53]
1 study · 96 participants
Very low

Potassium citrate vs no intervention

Retreatment · children with idiopathic urinary calculi treated with shockwave lithotripsy

The review found no eligible studies for this question.

1 finding from 1 review

Medical and dietary interventions for preventing recurrent urinary stones in children 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found