Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,752 questions · 6,648 findings · 688 reviews

No studies found 1,125 · 16.9%GRADE not reported 670 · 10.1%Very low 1,796 · 27%Low 1,685 · 25.3%Moderate 1,075 · 16.2%High 297 · 4.5%

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The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Fibroids · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance showed no clear difference in fibroids compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Abnormal Vaginal Bleeding or Spotting · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance probably leads to higher abnormal vaginal bleeding or spotting compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Breast cancer recurrence · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance showed no clear difference in breast cancer recurrence compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

The LNG‐IUS with endometrial surveillance vs endometrial surveillance alone

Breast Cancer‐related Death · endometrial protection in women with breast cancer on adjuvant tamoxifen

The LNG‐IUS with endometrial surveillance showed no clear difference in breast cancer‐related death compared with endometrial surveillance alone (moderate certainty).

1 finding from 1 review

Metal-free single crowns (full-contour zirconia) vs Cast gold (conventional metal) single crowns

Crown failure · Adults (18 years or older) needing a single crown in the molar or premolar region

It is very uncertain whether metal-free single crowns (full-contour zirconia) changes crown failure compared with cast gold (conventional metal) single crowns (very low certainty).

1 finding from 1 review

Metal-free single crowns (full-contour zirconia) vs Cast gold (conventional metal) single crowns

Crown complications · Adults (18 years or older) needing a single crown in the molar or premolar region

It is very uncertain whether metal-free single crowns (full-contour zirconia) changes crown complications compared with cast gold (conventional metal) single crowns (very low certainty).

2 findings from 1 review

Descemet’s membrane endothelial keratoplasty (DMEK) vs Descemet’s stripping automated endothelial keratoplasty (DSAEK)

Corneal graft dislocation any time pointa · participants/eyes with corneal endothelial failure

Descemet’s membrane endothelial keratoplasty (DMEK) may leads to higher corneal graft dislocation any time pointa compared with descemet’s stripping automated endothelial keratoplasty (DSAEK) (low certainty).

1 finding from 1 review

Pay for performance (P4P) plus existing payment methods vs existing payment methods

Quantity of service provision (dichotomous) ‐ child immunisation status up‐to‐date · healthcare providers working in outpatient healthcare settings

Pay for performance (P4P) plus existing payment methods probably leads to higher quantity of service provision (dichotomous) ‐ child immunisation… compared with existing payment methods (moderate certainty).

1 finding from 1 review

Pay for performance (P4P) plus existing payment methods vs existing payment methods

Quantity of service provision (continuous) ‐ immunisation rates for patients aged 65 years or older · healthcare providers working in outpatient healthcare settings

It is very uncertain whether pay for performance (P4P) plus existing payment methods changes quantity of service provision (continuous) ‐ immunisation rates for… compared with existing payment methods (very low certainty).

1 finding from 1 review

Pay for performance (P4P) plus existing payment methods vs existing payment methods

Quantity of service provision (continuous) ‐ number of detailed disease‐related consultation services per 100 prescriptions · healthcare providers working in outpatient healthcare settings

Pay for performance (P4P) plus existing payment methods may leads to higher quantity of service provision (continuous) ‐ number of detailed… compared with existing payment methods (low certainty).

1 finding from 1 review