Findings

What do systematic reviews say?

149 questions · 157 findings · 43 reviews · Airways

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No studies found 4 · 2.5%GRADE not reported 6 · 3.8%Very low 10 · 6.4%Low 71 · 45.2%Moderate 48 · 30.6%High 18 · 11.5%

Selexipag vs placebo

Dyspnea · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Prostacyclin vs control

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 868 participants
Low

Prostacyclin vs control

RAP · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1060 participants
Moderate

Prostacyclin vs control

Dyspnea · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1521 participants
Low

LABA/LAMA vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · Adults with COPD

1 finding from 1 review

Once daily long‐acting beta2‐agonists and long‐acting muscarinic antagonists in a combined inhaler versus placebo for… 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 4952 participants
High

Antibiotics vs placebo or usual care

Symptom score at 10 days. Measured on a 7‐point scale (0 to 6) ; lower score denotes fewer symptoms · acute asthma exacerbation

1 finding from 1 review

Antibiotics for exacerbations of asthma 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2 participants
Moderate

Summary of findings for AMBMT vs PR

Units of SGRQ change from baseline · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 249 participants
Low

Summary of findings for AMBMT vs PR

CAT score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 74 participants
Low

Summary of findings for AMBMT vs PR

Dyspnoea ‐ change in mMRC Scale 0 to 4. Lower is better and 1 unit is a clinically important difference · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 127 participants
Very low

Summary of findings for AMBMT vs PR

Change in dyspnoea score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 139 participants
Very low

Summary of findings for AMBMT + PR vs PR

Units of SGRQ change from baseline · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Active mind‐body movement therapies as an adjunct to or in comparison with pulmonary rehabilitation for people with… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 192 participants
Moderate

Combination inhaled therapy vs SABA

Health outcomes Peak expiratory flow readings (higher readings indicate better peak flow) · Adults with acute asthma

1 finding from 1 review

Combined inhaled beta‐agonist and anticholinergic agents for emergency management in adults with asthma 2017 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1056 participants
Moderate

Intervention not reported

Health‐related quality of life (respiratory specific) St George's Respiratory Questionnaire (SGRQ; total score) Scale from 0‐100 Lower value post intervention is favourable, indicating improvement in health‐related quality of life · people with stable COPD

1 finding from 1 review

Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 58 participants
Low

Intervention not reported

Breathlessness ‐ all trials Lower score indicates improvement in breathlessness · patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

1 finding from 1 review

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
no estimate extracted
32 studies · 865 participants
Low

Intervention not reported

Breathlessness ‐ subgroup analysis ‐ studies using short‐burst oxygen Lower score indicates improvement in breathlessness · patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

1 finding from 1 review

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 90 participants
Low

Intervention not reported

Breathlessness ‐ subgroup analysis ‐ studies not using short‐burst oxygen Lower score indicates improvement in breathlessness · patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

1 finding from 1 review

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
no estimate extracted
28 studies · 775 participants
Low

Intervention not reported

Breathlessness ‐ subgroup analysis ‐ studies measuring during exercise test Lower score indicates improvement in breathlessness · patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

1 finding from 1 review

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
no estimate extracted
30 studies · 591 participants
Moderate

Intervention not reported

Breathlessness ‐ subgroup analysis ‐ studies not measuring during exercise test Lower score indicates improvement in breathlessness · patients with chronic obstructive pulmonary disease who do not qualify for home oxygen therapy

1 finding from 1 review

Oxygen for breathlessness in patients with chronic obstructive pulmonary disease who do not qualify for home oxygen… 2016 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 274 participants
Low

Vilanterol and fluticasone furoate vs placebo

Health outcomes Peak expiratory flow readings (higher readings indicate better peak flow) · people with asthma

Vilanterol and fluticasone furoate showed no clear difference in peak expiratory flow compared with placebo (moderate certainty).

1 finding from 1 review

Vilanterol and fluticasone furoate for asthma 2016 · Cochrane Headline outcomes only
MD 33.3
2012 participants
Moderate

Intervention not reported

Asthma control (ACQ) Scale 0 to 6; lower is better12 months · adults or children with asthma

1 finding from 1 review

Remote versus face‐to‐face check‐ups for asthma 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 146 participants
Moderate