Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

163 questions · 171 findings · 22 reviews

No studies found 46 · 26.9%GRADE not reported 13 · 7.6%Very low 39 · 22.8%Low 59 · 34.5%Moderate 14 · 8.2%High 0 · 0%

Sulodexide (heparin plus dermatan sulphate chains) vs placebo

Days to resolution of pain / epithelialization; number of aphthae per month · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

Sulodexide (heparin plus dermatan sulphate chains) vs prednisone

Overall effectiveness (days to resolution; number of aphthae per month) · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review
  • A comparison between sulodexide (n=10) and prednisone (n=10) was made in a trial at high risk of bias (Femiano 2003). Data presented as ranges/totals only with no estimate of variability, precluding further analysis.…
    1 study · 20 participants
    GRADE not reported

Sulodexide (heparin plus dermatan sulphate chains) vs prednisone

Adverse effects · Participants with a previous or current history of recurrent aphthous stomatitis (RAS), diagnosed on history and clinical examination;…
1 finding from 1 review

Standard polyurethane plus sutureless securement devices vs standard polyurethane

Dislodgement assessed during catheter dwell · people with arterial catheter dressing and securement

It is very uncertain whether standard polyurethane plus sutureless securement devices changes dislodgement assessed during catheter dwell compared with standard polyurethane (very low certainty).

1 finding from 1 review

Integrated securement dressings vs standard polyurethane

Dislodgement assessed during catheter dwell · people with arterial catheter dressing and securement

Integrated securement dressings showed no clear difference in dislodgement assessed during catheter dwell compared with standard polyurethane (low certainty).

1 finding from 1 review

Standard polyurethane plus tissue adhesive vs standard polyurethane

Dislodgement assessed during catheter dwell · people with arterial catheter dressing and securement

It is very uncertain whether standard polyurethane plus tissue adhesive changes dislodgement assessed during catheter dwell compared with standard polyurethane (very low certainty).

1 finding from 1 review

Early intervention (mobilization or active exercise) vs usual care

Adverse events Proportion of participants with one or more events, or proportion of intervention sessions where an event occurred (falls, accidental dislodgement of attachments, haemodynamic instability, oxygen desaturation or any other adverse ev... · critically ill, mechanically ventilated adults
1 finding from 1 review

Bordered transparent dressing vs securement device

Dislodgement/accidental removal Observation · Patients requiring a peripheral venous catheter

It is very uncertain whether bordered transparent dressing changes dislodgement/accidental removal Observation compared with securement device (very low certainty).

1 finding from 1 review

Intravenous vs intraosseous route

Dislodgement of device during infusion · adults or children requiring fluid delivered by a parenteral route (one study testing insertion and the volume of fluid delivered in…

Intravenous showed no clear difference in dislodgement of device during infusion compared with intraosseous route (low certainty).

1 finding from 1 review