Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

472 questions · 500 findings · 31 reviews · Pregnancy and Childbirth

No studies found 126 · 25.2%GRADE not reported 48 · 9.6%Very low 105 · 21%Low 135 · 27%Moderate 63 · 12.6%High 23 · 4.6%

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Non‐initiation of breastfeeding · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

The review found no eligible studies for this question.

1 finding from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Exclusive breastfeeding at 4‐6 weeks · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

It is very uncertain whether physical breastfeeding support interventions (electric or manual… changes exclusive breastfeeding at 4‐6 weeks compared with usual care (no pump) (very low certainty).

1 finding from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Breastfeeding · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

It is very uncertain whether physical breastfeeding support interventions (electric or manual… changes any breastfeeding at 4‐6 weeks compared with usual care (no pump) (very low certainty).

2 findings from 1 review

Physical breastfeeding support interventions (electric or manual breast pump) vs usual care (no pump)

Exclusive breastfeeding at 6 months · women with a pre‐pregnancy BMI > 29 kg/m², who were intending to breastfeed, had no history of breast surgery, who were at least 19 years…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Social support vs less intensive interventions 9 · Pregnant women who smoke

The intervention showed no clear difference in social support vs less intensive interventions 9 (high certainty).

1 finding from 1 review

Pyridoxine vs placebo

Dizziness · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: dizziness compared with placebo (low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Adverse effects: headache · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: headaches compared with placebo (low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Interventions side effects: diarrhoea · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: diarrhoea compared with placebo; GRADE not reported.

1 finding from 1 review

Pyridoxine vs placebo

Adverse effects: palpitations · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: palpitations compared with placebo (low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Adverse effects: dry mouth · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: dry mouth compared with placebo (low certainty).

1 finding from 1 review

Tranexamic acid vs placebo/no treatment

Use of additional medical interventions to control PPH · pregnant women undergoing vaginal or caesarean birth who received TA for the prevention of postpartum haemorrhage

Tranexamic acid probably leads to lower use of additional medical interventions to control PPH compared with placebo/no treatment (moderate certainty).

1 finding from 1 review