Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

159 questions · 192 findings · 40 reviews · Tobacco Addiction

No studies found 8 · 4.2%GRADE not reported 1 · 0.5%Very low 56 · 29.2%Low 70 · 36.5%Moderate 43 · 22.4%High 14 · 7.3%

Intervention not reported

Nicotine patch · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in nicotine patch (low certainty).

1 finding from 1 review

Intervention not reported

Fast‐acting NRT (nicotine other) · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in fast‐acting NRT (nicotine other) (low certainty).

1 finding from 1 review

Intervention not reported

Bupropion · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in bupropion (moderate certainty).

1 finding from 1 review

Intervention not reported

Fast‐acting NRT (nicotine other) · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention leads to higher fast‐acting NRT (nicotine other) (high certainty).

1 finding from 1 review

Intervention not reported

Non‐nicotine/placebo EC · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention showed no clear difference in non‐nicotine/placebo EC (low certainty).

1 finding from 1 review

Intervention not reported

Nortriptyline · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…

The intervention probably leads to higher nortriptyline (moderate certainty).

1 finding from 1 review

Intervention not reported

Smoking cessation · people who have quit smoking using a cessation intervention

The intervention showed no clear difference in smoking cessation (moderate certainty).

1 finding from 1 review

Intervention not reported

NRT versus placebo Smoking cessation · people who have quit smoking using a cessation intervention

The intervention showed no clear difference in NRT versus placebo Smoking cessation (low certainty).

1 finding from 1 review

Intervention not reported

Bupropion versus placebo Smoking cessation · people who have quit smoking using a cessation intervention

The intervention showed no clear difference in bupropion versus placebo Smoking cessation (moderate certainty).

1 finding from 1 review