Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

336 questions · 357 findings · 36 reviews

No studies found 65 · 18.2%GRADE not reported 16 · 4.5%Very low 87 · 24.4%Low 114 · 31.9%Moderate 60 · 16.8%High 15 · 4.2%

Interferon + chemotherapy vs chemotherapy alone

Adverse event (flu‐like symptoms) · Women with advanced (Stage II‐IV) epithelial ovarian cancer who have undergone surgery

Interferon + chemotherapy showed no clear difference in adverse event (flu‐like symptoms) compared with chemotherapy alone (low certainty).

1 finding from 1 review

Interferon-alpha 1000 IU lozenges (topical) vs Interferon-alpha 2000 IU lozenges (topical)

Total ulcer burden · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care
1 finding from 1 review
  • Interventions for managing oral ulcers in Behçet's disease 2014 · Cochrane All outcomes
    Interferon-alpha dose comparison
    Kilic 2009 (interferon-alpha 1000 IU vs 2000 IU lozenges, 84 patients): the data presented did not allow analysis; authors reported no statistically significant difference in total ulcer burden between the two doses.
    1 study · 84 participants
    GRADE not reported