Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

130 questions · 130 findings · 13 reviews

No studies found 27 · 20.8%GRADE not reported 23 · 17.7%Very low 6 · 4.6%Low 38 · 29.2%Moderate 33 · 25.4%High 3 · 2.3%

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Hyperkalaemia · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in hyperkalaemia compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Death · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in death compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review

Non‐steroidal mineralocorticoid receptor antagonist vs selective aldosterone antagonist

Doubling serum creatinine · proteinuric chronic kidney disease

Non‐steroidal mineralocorticoid receptor antagonist showed no clear difference in doubling serum creatinine compared with selective aldosterone antagonist (low certainty).

1 finding from 1 review