Findings

What do systematic reviews say?

535 questions · 545 findings · 129 reviews · Headline outcomes only

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No studies found 131 · 24%GRADE not reported 30 · 5.5%Very low 123 · 22.6%Low 136 · 25%Moderate 98 · 18%High 27 · 5%

Rituximab (B cell) + steroid vs steroids

Failure of acute rejection reversal · kidney transplant recipients: first rejection episode

Rituximab (B cell) + steroid showed no clear difference in failure of reversal of acute rejection compared with steroid alone (moderate certainty).

1 finding from 1 review

Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients 2017 · Cochrane Headline outcomes only
RR 0.94 [0.54, 1.64]
2 studies · 53 participants
Moderate

Antibody (T cell) + steroid vs steroids

Failure of acute rejection reversal · kidney transplant recipients: first rejection episode

Antibody (T cell) + steroid showed no clear difference in failure of reversal of acute rejection episode compared with steroid alone (low certainty).

1 finding from 1 review

Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients 2017 · Cochrane Headline outcomes only
RR 0.42 [0.17, 1.01]
1 study · 30 participants
Low

Antibody (T cell) + steroid vs steroids

Recurrent rejection · kidney transplant recipients: first rejection episode

Antibody (T cell) + steroid showed no clear difference in recurrent rejection compared with steroid alone (low certainty).

1 finding from 1 review

Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients 2017 · Cochrane Headline outcomes only
RR 0.07 [0, 1.06]
1 study · 30 participants
Low

Oestrogen therapy alone vs no treatment or placebo

Subjective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs pelvic floor muscle training (PFMT)

Objective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs pelvic floor muscle training (PFMT)

Minor adverse effects: vaginal events · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs devices such

Subjective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs devices such

Objective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs devices such

Minor adverse effects: vaginal events · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs surgery

Subjective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs surgery

Objective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs surgery

Minor adverse effects: vaginal events · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs no treatment or placebo

Objective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs no treatment or placebo

Minor adverse effects: vaginal events · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oestrogen therapy alone vs pelvic floor muscle training (PFMT)

Subjective improvement or cure of POP symptoms · women with POP

The review found no eligible studies for this question.

1 finding from 1 review

Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Functional independence · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in functional independence at 3 months (mRS 0 to 2) (primary outcome) compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Different types of percutaneous endovascular interventions for acute ischemic stroke 2023 · Cochrane Headline outcomes only
RR 0.97 [0.82, 1.13]
2 studies · 633 participants
High

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Successful reperfusion (mTICI 2b to 3) postprocedure · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in successful reperfusion (mTICI 2b to 3) postprocedure compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Different types of percutaneous endovascular interventions for acute ischemic stroke 2023 · Cochrane Headline outcomes only
RR 1.01 [0.95, 1.07]
2 studies · 650 participants
High

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

All‐cause mortality within 3 months · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in all‐cause mortality within 3 months compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Different types of percutaneous endovascular interventions for acute ischemic stroke 2023 · Cochrane Headline outcomes only
RR 1.01 [0.74, 1.37]
2 studies · 633 participants
High

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Intracranial hemorrhage on imaging at 24 hours · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in intracranial hemorrhage on imaging at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Different types of percutaneous endovascular interventions for acute ischemic stroke 2023 · Cochrane Headline outcomes only
RR 1.03 [0.86, 1.24]
2 studies · 645 participants
High

Thrombo‐aspiration alone vs stent‐retrieval thrombectomy alone

Symptomatic intracranial haemorrhage at · people with acute ischemic stroke

Thrombo‐aspiration alone showed no clear difference in symptomatic intracranial hemorrhage at 24 hours compared with stent‐retrieval thrombectomy alone (high certainty).

1 finding from 1 review

Different types of percutaneous endovascular interventions for acute ischemic stroke 2023 · Cochrane Headline outcomes only
RR 0.9 [0.49, 1.68]
2 studies · 645 participants
High