Serious adverse events (nosocomial infection) (penicillin versus doxycycline) · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (penicillin versus… compared with other antibiotics (very low certainty).
1 finding from 1 review
Serious adverse events (nosocomial infection) (doxycycline versus cefotaxime) · people with leptospirosis
It is very uncertain whether summary of findings table ‐ Antibiotics changes serious adverse events (nosocomial infection) (doxycycline versus… compared with other antibiotics (very low certainty).
1 finding from 1 review
Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID
It is very uncertain whether regimens containing macrolides (azithromycin) changes clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (very low certainty).
2 findings from 1 review
RR 1.18 [0.89, 1.55]
Studies not reported
Very low
RR 1.35 [1.1, 1.67]
Studies not reported
Moderate
Clinical cure according to criteria established by study authors Severe PID · women with PID
Regimens containing macrolides (azithromycin) showed no clear difference in clinical cure according to criteria established by study authors… compared with regimens containing tetracycline (doxycycline) (low certainty).
1 finding from 1 review
RR 1 [0.96, 1.05]
Studies not reported
Low
Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID
Regimens containing macrolides (azithromycin) showed no clear difference in adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing tetracycline (doxycycline) (low certainty).
1 finding from 1 review
RR 0.71 [0.38, 1.34]
Studies not reported
Low
Microbiological clearance · women with PID
Regimens containing macrolides (azithromycin) showed no clear difference in microbiological clearance compared with regimens containing tetracycline (doxycycline); GRADE not reported.
1 finding from 1 review
RR 1.02 [0.98, 1.06]
Studies not reported
GRADE not reported
Laparoscopic evidence of resolution of PID based on physician opinion · women with PID
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Length of stay · women with PID
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Fertility outcome · women with PID
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Total studies: 55* Total participants: 3758 No. interventions in network: 21 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
The intervention led to lower total studies: 55* Total participants: 3758 No. interventions in…; GRADE not reported.
1 finding from 1 review
no estimate extracted
55 participants
GRADE not reported
Intervention not reported
Talc poudrage (4 RCTs; 553 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Bleomycin (14 RCTs; 774 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
IPC – not daily drainage (1 RCT; 101 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Placebo (2 RCTs; 118 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Total studies: 31* Total participants: 2753 No. interventions in network: 14 · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…
The intervention led to lower total studies: 31* Total participants: 2753 No. interventions in…; GRADE not reported.
1 finding from 1 review
no estimate extracted
31 participants
GRADE not reported
Intervention not reported
Talc slurry (9 RCTs, 1320 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Talc poudrage (4 RCTs, 886 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Bleomycin (13 RCTs, 724 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
IPC – not daily drainage (6 RCTs, 738 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review
Intervention not reported
Talc slurry (19 RCTs, 907 participants) · adults with malignant pleural effusion Interventions: talc poudrage, bleomycin, IPC – not daily drainage, doxycycline, placebo Comparator…
1 finding from 1 review