Calcium-enriched mixture (CEM) cement vs Mineral trioxide aggregate (MTA)
- No radiological failure in any participant at 6 months; not estimable1 study · 42 participantsVery low
- RR 0.33 [0.04, 2.94]1 study · 80 participantsGRADE not reported
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with glutaraldehyde + zinc oxide and eugenol (ZOE); GRADE not reported.
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in clinical failure compared with full strength formocresol (FC); GRADE not reported.
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in radiological failure compared with full strength formocresol (FC); GRADE not reported.
Glutaraldehyde + calcium hydroxide (CH) showed no clear difference in clinical failure compared with glutaraldehyde + zinc oxide and eugenol (ZOE); GRADE not reported.
Partial pulpotomy with calcium hydroxide had a pooled success rate of 34.3%.
Calcium hydroxide/iodoform (CH/iodoform) led to higher radiological failure compared with full strength formocresol (FC); GRADE not reported.
Calcium hydroxide/iodoform (CH/iodoform) led to higher clinical failure compared with full strength formocresol (FC); GRADE not reported.
Sealapex (eugenol-free calcium hydroxide) showed no clear difference in radiological failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.
Sealapex (eugenol-free calcium hydroxide) showed no clear difference in clinical failure compared with zinc oxide and eugenol (ZOE); GRADE not reported.
Electrofulguration + calcium hydroxide (CH) showed no clear difference in clinical failure compared with electrofulguration + zinc oxide and eugenol (ZOE); GRADE not reported.
Electrofulguration + calcium hydroxide (CH) showed no clear difference in radiological failure compared with electrofulguration + zinc oxide and eugenol (ZOE); GRADE not reported.
Low-level laser therapy (LLLT) + calcium hydroxide showed no clear difference in radiological failure compared with formocresol (FC); GRADE not reported.
Calcium sulphate grafting of the periapical lesion showed no clear difference in healing - 1 year compared with no grafting (low certainty).
Partial pulpotomy with MTA or Biodentine had a pooled success rate of 86.8%.
The effect of material choice (MTA vs CaOH) on postoperative pain is unclear: two small studies used different methods and reported contradictory results, so no meta-analysis was performed (ungraded).
Biodentine and calcium hydroxide did not differ significantly in clinical and radiographic success (OR 3.14, 95% CI 0.91 to 10.86; ungraded subgroup analysis).
Mineral trioxide aggregate shows higher odds of clinical and radiographic success than calcium hydroxide (OR 3.05, 95% CI 1.70 to 5.45; ungraded subgroup analysis).
In partial pulpotomy, MTA had significantly higher success than calcium hydroxide (OR 2.81; ungraded).