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Evidence found and GRADE certainty

89 questions · 91 findings · 37 reviews · Musculoskeletal

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No studies found 42 · 46.2%GRADE not reported 6 · 6.6%Very low 3 · 3.3%Low 25 · 27.5%Moderate 12 · 13.2%High 3 · 3.3%

Canakinumab vs triamcinolone acetonide

Global assessment of treatment success · acute gout

Canakinumab probably leads to higher participant global assessment of response to treatment: good or… compared with triamcinolone acetonide (moderate certainty).

1 finding from 1 review

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to higher global assessment of treatment success "Success, much improved,… compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher global assessment of treatment success "Disappearance of shoulder… compared with oral NSAID (low certainty).

1 finding from 1 review

Manual therapy and exercise vs glucocorticoid injection

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise probably leads to lower global assessment of treatment success Complete recovery or much… compared with glucocorticoid injection (moderate certainty).

1 finding from 1 review

Intervention not reported

Reduction in disability score Health Assessment Questionnaire (mean improvement from baseline). Scale from: 0 to 3 · participants with rheumatoid arthritis and with partial response to MTX
1 finding from 1 review

Intervention not reported

Reduction in disability score Health Assessment Questionnaire. Scale from: 0 to 3 · participants with rheumatoid arthritis and with a partial response to DMARDs
1 finding from 1 review

Posterior cruciate ligament retention vs sacrifice (using the same arthroplasty design)

Global assessment (patient) Patient satisfaction on scale 0 (not at all satisfied) to 10 (completely satisfied) · Patients receiving total knee arthroplasty with or without resection of the posterior cruciate ligament for the treatment of osteoarthritis
1 finding from 1 review

Posterior cruciate ligament retention vs posterior stabilised sacrifice

Global Assessment (Patient) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

Posterior cruciate ligament retention vs sacrifice (all types of arthroplasty designs)

Global assessment (patient) Patient satisfaction on scale 0 (not at all satisfied) to 10 (completely satisfied) · Patients receiving total knee arthroplasty with or without posterior stabilised design for the treatment of osteoarthritis
1 finding from 1 review

Intervention not reported

Patient global assessment ‐ not measured · patients with acute gout

The review found no eligible studies for this question.

1 finding from 1 review