Remission · treatment‐resistant depression in adults
Augmentation of current antidepressant (various) with quetiapine… probably leads to higher remission (MADRS score ≤ 8/HAM‐D score ≤ 7) ‐ Any dose compared with augmentation of current antidepressant (various) with placebo (moderate certainty).
1 finding from 1 review
Quality of life (% max score of Q‐LES‐Q‐SF) ‐ Any dose Scale from: 0 to 100 (better) · treatment‐resistant depression in adults
1 finding from 1 review
Depressive symptoms · treatment‐resistant depression in adults
1 finding from 1 review
Dropouts ‐ Any dose · treatment‐resistant depression in adults
Augmentation of current antidepressant (SSRI) with ziprasidone (40… probably leads to higher dropouts ‐ Any dose compared with augmentation of current antidepressant (SSRI) with placebo or… (moderate certainty).
1 finding from 1 review
Response (≥ 50% reduction in MADRS or HAM‐D score) ‐ Any dose · treatment‐resistant depression in adults
Augmentation of current antidepressant (SSRI) with ziprasidone (40… probably leads to higher response (≥ 50% reduction in MADRS/HAM‐D score) ‐ Any dose compared with augmentation of current antidepressant (SSRI) with placebo or… (moderate certainty).
1 finding from 1 review
Remission · treatment‐resistant depression in adults
Augmentation of current antidepressant (SSRI) with ziprasidone (40… showed no clear difference in remission (clinician‐rated) ‐ Any dose compared with augmentation of current antidepressant (SSRI) with placebo or… (moderate certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
All psychological therapies showed no clear difference in dropouts for any reason compared with other antidepressants (low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
It is very uncertain whether all psychological therapies changes dropouts for any reason compared with benzodiazepines (very low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
It is very uncertain whether all psychological therapies changes dropouts for any reason compared with antidepressants alone or antidepressants and benzodiazepines (very low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
All psychological therapies showed no clear difference in dropouts for any reason compared with SSRI (low certainty).
1 finding from 1 review
Leaving the study early · adults with panic disorder
All psychological therapies showed no clear difference in dropouts for any reason compared with tricyclic antidepressants (low certainty).
1 finding from 1 review
Intervention not reported
Prevalence of psychological trauma (short term: up to 3 months postpartum) Measured by various scales ‐ Impact of Event Scale (IES), MINI‐PTSD · Women of any age who had given birth within one month of the intervention being offered
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Prevalence of depression or depressive symptoms (short term: up to 3 months postpartum) Measured by various scales ‐ EPDS, HADS · Women of any age who had given birth within one month of the intervention being offered
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Prevalence of anxiety (short term: up to 3 months postpartum) Measured by HADS · Women of any age who had given birth within one month of the intervention being offered
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Prevalence of fear of childbirth (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Prevalence of general psychological morbidity (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Health service utilization (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Attrition from treatment (short term: up to 3 months postpartum) · Women of any age who had given birth within one month of the intervention being offered
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Depression response or remission (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events · women of any age, with PND up to 12 months
Antidepressants may leads to lower adverse events compared with psychological interventions (low certainty).
1 finding from 1 review
no estimate extracted
Studies not reported
Low