Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

131 questions · 131 findings · 10 reviews

No studies found 22 · 16.8%GRADE not reported 9 · 6.9%Very low 22 · 16.8%Low 37 · 28.2%Moderate 29 · 22.1%High 12 · 9.2%

Intervention not reported

28‐day all‐cause mortality · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention probably leads to lower 28‐day all‐cause mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

Quality of life up to longest · non‐hospitalised adults with mild COVID‐19

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Thrombotic events up to day 45 · non‐hospitalised adults with mild COVID‐19

The intervention showed no clear difference in thrombotic events up to day 45 (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events during study treatment · non‐hospitalised adults with mild COVID‐19

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Serious adverse events up to day 45 · non‐hospitalised adults with mild COVID‐19

The intervention showed no clear difference in serious adverse events up to day 45 (low certainty).

1 finding from 1 review

Intervention not reported

Worsening up to day 28: participants with new need for invasive mechanical ventilation or death · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention showed no clear difference in worsening up to day 28: participants with new need for invasive… (moderate certainty).

1 finding from 1 review

Intervention not reported

Improvement up to day 28: participants discharged alive · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention showed no clear difference in improvement up to day 28: participants discharged alive (moderate certainty).

1 finding from 1 review

Intervention not reported

Thrombotic events at longest · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention showed no clear difference in thrombotic events at longest (moderate certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events at longest · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention showed no clear difference in serious adverse events at longest (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events during study treatment · hospitalised adults with COVID‐19 (moderate to severe disease)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Major bleeding events at longest · hospitalised adults with COVID‐19 (moderate to severe disease)

The intervention probably leads to higher major bleeding events at longest (moderate certainty).

1 finding from 1 review

Intervention not reported

All‐cause mortality at day 45 · non‐hospitalised adults with mild COVID‐19

The intervention showed no clear difference in all‐cause mortality at day 45 (low certainty).

1 finding from 1 review