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Evidence found and GRADE certainty

107 questions · 108 findings · 7 reviews

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No studies found 30 · 27.8%GRADE not reported 6 · 5.6%Very low 15 · 13.9%Low 41 · 38%Moderate 12 · 11.1%High 4 · 3.7%

Loratadine 10 mg vs placebo (4‐week intervention)

Primary outcome 2. Proportion of participants reporting adverse effects and serious adverse events throughout the study period · adults with eczema

Loratadine 10 mg/d showed no clear difference in primary outcome 2. Proportion of participants reporting adverse… compared with placebo (4‐week intervention) (low certainty).

1 finding from 1 review

Cetirizine 0.5 mg/kg/d vs placebo (18‐month intervention)

Primary outcome 2. Proportion of participants reporting adverse effects and serious adverse events throughout the study period · children with eczema

Cetirizine 0.5 mg/kg/d showed no clear difference in primary outcome 2. Proportion of participants reporting adverse… compared with placebo (18‐month intervention) (moderate certainty).

1 finding from 1 review

Loratadine 10 mg vs placebo (2‐week intervention)

Secondary outcome 1. Physician‐assessed clinical signs Number for whom treatment success was judged as good or very good · adults with eczema

Loratadine 10 mg/d showed no clear difference in secondary outcome 1. Physician‐assessed clinical signs Number for… compared with placebo (2‐week intervention) (low certainty).

1 finding from 1 review

Cetirizine 10 mg/d vs placebo (4‐week intervention)

Primary outcome 2. Proportion of participants reporting adverse effects and serious adverse events throughout the study period · adults with eczema

Cetirizine 10 mg/d showed no clear difference in primary outcome 2. Proportion of participants reporting adverse… compared with placebo (4‐week intervention) (low certainty).

1 finding from 1 review