Question · asked by 1 review

Cetirizine 10 mg/d vs placebo (4‐week intervention): Physician‐assessed changes in clinical signs

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Cetirizine 10 mg/d vs placebo (4‐week intervention)
Secondary outcome 1. Mean change in physician‐assessed clinical signs Total sum of 4 symptoms (signs) scores, each measured on 4‐point Likert scale (0 = absent; 3 = severe) · adults with eczema
Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema (2019) · Cochrane Headline outcomes only
no estimate extracted1 study · 84 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Oral H1 antihistamines as ‘add‐on’ therapy to topical treatment for eczema
2019 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.