Findings

What do systematic reviews say?

85 questions · 86 findings · 9 reviews · Eyes and Vision

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No studies found 37 · 43%GRADE not reported 3 · 3.5%Very low 15 · 17.4%Low 18 · 20.9%Moderate 11 · 12.8%High 2 · 2.3%

Antibiotics vs control

Antibiotic resistance · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs control

Adverse effects · people (any age) with active trachoma

Antibiotic may leads to lower adverse effects compared with control (low certainty).

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 1961 participants
Low

Oral vs topical antibiotics

Active trachoma · people (any age) with active trachoma

Oral showed no clear difference in active trachoma Clinical assessment: active trachoma defined as TF,… compared with topical antibiotic (low certainty).

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
RR 0.97 [0.81, 1.16]
6 studies · 953 participants
Low

Oral vs topical antibiotics

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 298 participants
Very low

Oral vs topical antibiotics

Antibiotic resistance · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Oral vs topical antibiotics

Adverse effects · people (any age) with active trachoma

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 1583 participants
Low

Oral azithromycin vs control

Active trachoma · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Comparison (intervention vs comparator) · participants undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Treatment 2: topical regimen alone (chloramphenicol‐sulfadimidine) · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
6618 participants
Moderate

Intervention not reported

Mode 1: Anterior sub‐Tenon injections (subconjunctival) · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
77015 participants
Moderate

Intervention not reported

Mode 2: Posterior sub‐Tenon injections (retrobulbar) · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
77015 participants
Moderate

Intervention not reported

Treatment 1: fixed combination of topical gatifloxacin 0.3% and prednisolone acetate 1% · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
108 participants
Very low

Intervention not reported

Treatment 2: individual instillation of topical gatifloxacin 0.3% and prednisolone acetate 1% · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
108 participants
Very low

Intervention not reported

Control: BSS‐only irrigating infusion fluid · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
644 participants
Very low

Intervention not reported

Treatment 1: combined intracameral cefuroxime and topical levofloxacin · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
16603 participants
High

Intervention not reported

Treatment 2: intracameral cefuroxime 0.9% · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
16603 participants
High

Intervention not reported

Treatment 3: topical levofloxacin 0.5% · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
16603 participants
Moderate

Intervention not reported

Control: placebo drops · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
16603 participants
Moderate

Intervention not reported

Interventions · participants undergoing cataract surgery

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Treatment 1: combined prophylaxis (topical regimen + periocular penicillin at the time of surgery) · participants undergoing cataract surgery

1 finding from 1 review

Perioperative antibiotics for prevention of acute endophthalmitis after cataract surgery 2017 · Cochrane Headline outcomes only
no estimate extracted
6618 participants
Moderate