Findings

What do systematic reviews say?

132 questions · 139 findings · 9 reviews · ENT

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No studies found 57 · 41%GRADE not reported 0 · 0%Very low 56 · 40.3%Low 21 · 15.1%Moderate 5 · 3.6%High 0 · 0%

Antibiotics vs no treatment/placebo

Ear pain (otalgia) or discomfort or local irritation · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment/placebo

Hearing · children with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Antibiotics vs no treatment/placebo

Serious complications ‐ during 6 months of · children with CSOM

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Antibiotics vs no treatment/placebo

Suspected ototoxicity · children with CSOM

The review found no eligible studies for this question.

1 finding from 1 review

Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs boric acid

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs boric acid

Ear pain (otalgia) or discomfort or local irritation · chronic suppurative otitis media

Topical antibiotics (quinolones) may leads to lower ear pain, discomfort, irritation compared with boric acid (low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 0.56 [0.32, 0.98]
2 studies · 510 participants
Low

Topical quinolone vs boric acid

Average change in hearing from baseline · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 390 participants
Low

Topical quinolone vs boric acid

Serious complications ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs boric acid

Suspected ototoxicity ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs povidone‐iodine

Resolution of ear discharge ‐ measured at 1 to 2 weeks · chronic suppurative otitis media

It is very uncertain whether topical antibiotics (quinolones) changes resolution of ear discharge (1 to 2 weeks) compared with povidone‐iodine (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 1.02 [0.82, 1.26]
1 study · 39 participants
Very low

Topical quinolone vs povidone‐iodine

Resolution of ear discharge ‐ measured after 4 weeks · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs povidone‐iodine

Quality of life ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs povidone‐iodine

Ear pain (otalgia) or discomfort or local irritation · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs povidone‐iodine

Hearing · chronic suppurative otitis media

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Topical quinolone vs povidone‐iodine

Serious complications ‐ not measured · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical quinolone vs povidone‐iodine

Suspected ototoxicity · chronic suppurative otitis media

It is very uncertain whether topical antibiotics (quinolones) changes suspected ototoxicity compared with povidone‐iodine (very low certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Very low

Topical quinolone vs boric acid

Resolution of ear discharge (1 to 2 weeks) Quinolones · chronic suppurative otitis media

Topical antibiotics (quinolones) probably leads to higher resolution of ear discharge (1 to 2 weeks) Quinolones compared with boric acid (moderate certainty).

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 1.86 [1.48, 2.35]
1 study · 411 participants
Moderate

Topical quinolone vs boric acid

Resolution of ear discharge ‐ measured after 4 weeks · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics versus topical antiseptics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics with steroids vs placebo/no treatment

Resolution of ear discharge ‐ measured at 1 to 2 weeks · chronic suppurative otitis media

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics with steroids vs placebo/no treatment

Resolution of ear discharge ‐ measured after 4 weeks · chronic suppurative otitis media

1 finding from 1 review

Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low