Findings

What do systematic reviews say?

72 questions · 72 findings · 12 reviews · Anaesthesia

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No studies found 1 · 1.4%GRADE not reported 6 · 8.3%Very low 24 · 33.3%Low 18 · 25%Moderate 20 · 27.8%High 3 · 4.2%

Nitroglycerin vs no treatment

Hypotension · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Nitroglycerin vs no treatment

Adverse effects: headache · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes side effect (headache) compared with no treatment (very low certainty).

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
RR 3.67 [0.14, 96.14]
2 studies · 6629 participants
Very low

Nitroglycerin vs placebo

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with placebo (very low certainty).

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
RR 2.81 [0.12, 63.83]
2 studies · 89 participants
Very low

Nitroglycerin vs placebo

Acute myocardial infarction · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes acute myocardial infarction compared with placebo (very low certainty).

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
RR 4.69 [0.24, 89.88]
1 study · 29 participants
Very low

Nitroglycerin vs placebo

Angina · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

NPPV vs oxygen therapy

Hospital mortality · adults (aged > 17 years) with acute respiratory failure after upper abdominal surgery

Noninvasive positive pressure ventilation (NPPV) showed no clear difference in hospital mortality compared with oxygen therapy (low certainty).

1 finding from 1 review

Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery 2015 · Cochrane Headline outcomes only
RR 0.14 [0.01, 2.71]
1 study · 209 participants
Low

NPPV vs oxygen therapy

Rate of intubation · adults (aged > 17 years) with acute respiratory failure after upper abdominal surgery

Noninvasive positive pressure ventilation (NPPV) may leads to lower rate of tracheal Intubation compared with oxygen therapy (low certainty).

1 finding from 1 review

Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery 2015 · Cochrane Headline outcomes only
RR 0.25 [0.08, 0.83]
2 studies · 269 participants
Low

NPPV vs oxygen therapy

Duration of ICU stay · adults (aged > 17 years) with acute respiratory failure after upper abdominal surgery

It is very uncertain whether noninvasive positive pressure ventilation (NPPV) changes ICU length of stay compared with oxygen therapy (very low certainty).

1 finding from 1 review

Noninvasive positive pressure ventilation for acute respiratory failure following upper abdominal surgery 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 269 participants
Very low

Intervention not reported

Arrhythmias ‐ by drug type in all patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
57 studies · 2902 participants
Moderate

Intervention not reported

Arrhythmias ‐ high risk patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 337 participants
Moderate

Intervention not reported

Myocardial Ischaemia ‐ by drug type in all patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
30 studies · 1636 participants
Low

Intervention not reported

Myocardial Ischaemia ‐ high risk patients · Adult patients 18 years and above undergoing elective surgery

1 finding from 1 review

Pharmacological agents for preventing morbidity associated with the haemodynamic response to tracheal intubation 2013 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 395 participants
Moderate