What do systematic reviews say?

IV or oral iron alone vs no treatment

IV or oral iron alone showed no clear difference in on‐study mortality3 (Subnet based on 55 studies including 15,074… compared with no treatment (low certainty).

• Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer… 2022 · Cochrane Headline outcomes only
  RR 2.95 [0.71, 12.34]
  Studies not reported
  Low

IV or oral iron alone vs no treatment

The review found no eligible studies for this question.

• Intravenous iron versus oral iron versus no iron with or without erythropoiesis‐ stimulating agents (ESA) for cancer… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Tramadol vs placebo

The review found no eligible studies for this question.

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Tramadol vs paracetamol

The review found no eligible studies for this question.

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Tramadol vs paracetamol

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 20 participants
  Very low

Tramadol vs paracetamol

The review found no eligible studies for this question.

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Tramadol vs NSAIDs

The review found no eligible studies for this question.

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Tramadol vs placebo

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 3972 participants
  Moderate

Tramadol vs NSAIDs

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 952 participants
  Moderate

Tramadol vs NSAIDs

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 952 participants
  Low

Tramadol vs other opioids

The review found no eligible studies for this question.

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Tramadol vs other opioids

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 411 participants
  Moderate

Tramadol vs other opioids

Tramadol alone probably leads to higher physical function compared with other opioids (moderate certainty).

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  RR 1.32 [1.04, 1.68]
  1 study · 190 participants
  Moderate

Tramadol vs placebo

• Tramadol for osteoarthritis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 2550 participants
  Moderate

Oestrogen therapy alone vs pelvic floor muscle training (PFMT)

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oestrogen therapy alone vs devices such

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oestrogen therapy alone vs surgery

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Oestrogen therapy alone vs no treatment or placebo

The review found no eligible studies for this question.

• Oestrogen therapy for treating pelvic organ prolapse in postmenopausal women 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

HAART + liposomal anthracycline vs HAART alone

HAART + liposomal anthracycline showed no clear difference in kaposi's sarcoma IRIS compared with HAART alone (moderate certainty).

• Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults 2014 · Cochrane Headline outcomes only
  RR 0.49 [0.16, 1.55]
  1 study · 129 participants
  Moderate

HAART + liposomal anthracycline vs HAART alone

HAART + liposomal anthracycline showed no clear difference in mortality compared with HAART alone (moderate certainty).

• Treatment of severe or progressive Kaposi's sarcoma in HIV‐infected adults 2014 · Cochrane Headline outcomes only
  RR 1.23 [0.35, 4.38]
  1 study · 129 participants
  Moderate