Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,268 questions · 1,343 findings · 197 reviews

No studies found 317 · 23.6%GRADE not reported 189 · 14.1%Very low 356 · 26.5%Low 271 · 20.2%Moderate 173 · 12.9%High 37 · 2.8%

Intervention not reported

Number of patients with at least one bleeding episode of any severity · patients with solid tumours without thrombocytopenia before chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one bleeding episode of any severity (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with at least one severe/life‐threatening bleeding episode · patients with solid tumours without thrombocytopenia before chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one severe/life‐threatening… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of patients with at least one bleeding episode of any severity · patients with solid tumours with thrombocytopenia during chemotherapy

It is very uncertain whether the intervention changes number of patients with at least one bleeding episode of any severity (very low certainty).

1 finding from 1 review

Untargeted antifungal treatment with any antifungal drug (systemic or nonabsorbable) vs Placebo, no treatment, or another active antifungal intervention

Total (all‐cause) mortality · preventing fungal infections in non‐neutropenic critically ill patients

Untargeted antifungal treatment with any antifungal drug (systemic… showed no clear difference in total (all‐cause) mortality compared with placebo/no antifungal/any other antifungal (moderate certainty).

1 finding from 1 review

Untargeted antifungal treatment with any antifungal drug (systemic or nonabsorbable) vs Placebo, no treatment, or another active antifungal intervention

Proven invasive fungal infection · preventing fungal infections in non‐neutropenic critically ill patients

Untargeted antifungal treatment with any antifungal drug (systemic… may leads to lower proven invasive fungal infection compared with placebo/no antifungal/any other antifungal (low certainty).

1 finding from 1 review

Untargeted antifungal treatment with any antifungal drug (systemic or nonabsorbable) vs Placebo, no treatment, or another active antifungal intervention

Superficial fungal infection · preventing fungal infections in non‐neutropenic critically ill patients

Untargeted antifungal treatment with any antifungal drug (systemic… showed no clear difference in superficial fungal infection compared with placebo/no antifungal/any other antifungal (low certainty).

1 finding from 1 review

Untargeted antifungal treatment with any antifungal drug (systemic or nonabsorbable) vs Placebo, no treatment, or another active antifungal intervention

Fungal colonization · preventing fungal infections in non‐neutropenic critically ill patients

Untargeted antifungal treatment with any antifungal drug (systemic… may leads to lower fungal colonization compared with placebo/no antifungal/any other antifungal (low certainty).

1 finding from 1 review

Untargeted antifungal treatment with any antifungal drug (systemic or nonabsorbable) vs Placebo, no treatment, or another active antifungal intervention

Treatment cessation due to adverse events · preventing fungal infections in non‐neutropenic critically ill patients

Untargeted antifungal treatment with any antifungal drug (systemic… showed no clear difference in adverse events requiring cessation of study drug(s) compared with placebo/no antifungal/any other antifungal (low certainty).

1 finding from 1 review