Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Ocrelizumab vs placebo

Number of participants with new or enlarging T2‐hyperintense lesions on MRI · primary progressive multiple sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Ocrelizumab vs interferon beta‐1a

Number of participants with new or enlarging T2‐hyperintense lesions on MRI · patients with relapsing‐remitting multiple sclerosis

Ocrelizumab may leads to lower number of participants with new or enlarging T2‐hyperintense lesions… compared with interferon beta‐1a (low certainty).

1 finding from 1 review

Mindfulness vs control

Smoking cessation · people who smoke

Mindfulness training showed no clear difference in mindfulness training vs matched‐intensity smoking cessation… compared with control (low certainty).

2 findings from 1 review