Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,793 questions · 1,866 findings · 339 reviews

No studies found 245 · 13.1%GRADE not reported 142 · 7.6%Very low 612 · 32.8%Low 513 · 27.5%Moderate 305 · 16.3%High 49 · 2.6%

Yoga vs NON‐STANDARD CARE

Behaviour: Leaving the study early (short‐term) · patients with schizophrenia

YOGA probably leads to lower leaving the study early: short term compared with NON‐STANDARD CARE (moderate certainty).

1 finding from 1 review

Celecoxib vs NSAIDs

Short‐term serious adverse events · patients with rheumatoid arthritis

Celecoxib showed no clear difference in short‐term serious adverse events compared with traditional NSAIDs (low certainty).

1 finding from 1 review

Celecoxib vs placebo

Short‐term serious adverse events · patients with rheumatoid arthritis

Celecoxib showed no clear difference in short‐term serious adverse events compared with placebo (low certainty).

1 finding from 1 review

WENDAN DECOCTION vs placebo or no treatment

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION may leads to lower global state: Clinically important change ‐ no improvement ‐ defined… compared with PLACEBO OR NO TREATMENT (low certainty).

1 finding from 1 review

WENDAN DECOCTION vs antipsychotics

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

WENDAN DECOCTION probably leads to lower adverse effects: Movement disorders ‐ Extra Pyramidal Symptoms… compared with ANTIPSYCHOTIC DRUG (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION PLUS NORMAL DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION PLUS NORMAL DOSE ANTIPSYCHOTIC probably leads to lower global state: Clinically important change ‐ no improvement ‐ defined… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION PLUS NORMAL DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

WENDAN DECOCTION PLUS NORMAL DOSE ANTIPSYCHOTIC probably leads to lower adverse effects: Movement disorders ‐ Extra Pyramidal Symptoms… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC probably leads to lower global state: Clinically important change ‐ no improvement ‐ defined… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC vs STANDARD DOSE ANTIPSYCHOTICS

Adverse effects: any observed extrapyramidal symptoms ‐ short term (up to 6 months) · patients with schizophrenia

WENDAN DECOCTION PLUS LOW DOSE ANTIPSYCHOTIC probably leads to lower adverse effects: Movement disorders ‐ Extra Pyramidal Symptoms… compared with NORMAL DOSE ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

WENDAN DECOCTION vs antipsychotics

Global state: Clinically important change ‐ no improvement ‐ defined as PANSS < 50% reduction (short term) · patients with schizophrenia

WENDAN DECOCTION showed no clear difference in global state: Clinically important change ‐ no improvement ‐ defined… compared with ANTIPSYCHOTIC DRUG (moderate certainty).

1 finding from 1 review