Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,017 questions · 1,061 findings · 131 reviews

No studies found 193 · 18.2%GRADE not reported 65 · 6.1%Very low 237 · 22.3%Low 325 · 30.6%Moderate 187 · 17.6%High 54 · 5.1%

Foley catheter vs intravenous (IV) oxytocin

Vaginal delivery not achieved within 24 hours · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in vaginal delivery not achieved within 24 hours compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Uterine hyperstimulation with fetal heart rate changes · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in uterine hyperstimulation with fetal heart rate changes compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Caesarean section · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in caesarean section compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Caesarean section · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in caesarean section compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious neonatal morbidity or perinatal death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious neonatal morbidity/perinatal death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious maternal morbidity or death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious maternal morbidity or death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Perineural vs intravenous dexamethasone

Incidence of serious adverse events (we used the NIH definition of adverse events. A serious event includes death, a life‐threatening event that requires hospitalization or prolonged hospitalization, disability or congenital anomaly) · peripheral nerve block

The review found no eligible studies for this question.

1 finding from 1 review

Perineural vs intravenous dexamethasone

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · peripheral nerve block
3 findings from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Adverse events · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery

It is very uncertain whether perioperative infraorbital nerve block changes pain measured by valid instruments (mean postoperative pain score) compared with intravenous analgesia (very low certainty).

1 finding from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block may leads to lower time to feeding after surgery (in minutes) compared with intravenous analgesia (low certainty).

1 finding from 1 review