Imiquimod showed no clear difference in medium‐term clinical cure (after 3 months and up to 6 months after… compared with vehicle (moderate certainty).
Imiquimod showed no clear difference in long‐term clinical cure (beyond 6 months after start of treatment)… compared with vehicle (moderate certainty).
Imiquimod showed no clear difference in short‐term clinical improvement (up to 3 months after start of… compared with vehicle (high certainty).
Imiquimod showed no clear difference in any adverse effect compared with vehicle (high certainty).
Imiquimod probably leads to higher application site reactions compared with vehicle (moderate certainty).
Imiquimod probably leads to higher severe application site reactions compared with vehicle (moderate certainty).
The review found no eligible studies for this question.
It is very uncertain whether paromomycin ointment changes microbiological or histopathological cure of skin lesions compared with vehicle (very low certainty).
It is very uncertain whether itraconazole (200 mg for 6 to 8 weeks) changes percentage of participants with complete cure compared with placebo (very low certainty).
It is very uncertain whether itraconazole (200 mg for 6 to 8 weeks) changes adverse effects Mild abdominal pain and nausea Adverse effects Mild… compared with placebo (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether itraconazole (200 mg for 6 to 8 weeks) changes microbiological or histopathological cure of skin lesions compared with placebo (very low certainty).
The review found no eligible studies for this question.
It is very uncertain whether paromomycin ointment changes percentage of participants with complete cure compared with vehicle (very low certainty).
It is very uncertain whether paromomycin ointment changes adverse effects Skin/local reactions compared with vehicle (very low certainty).
The review found no eligible studies for this question.
Antibiotic prophylaxis probably leads to lower recurrence of cellulitis compared with no treatment/placebo (moderate certainty).
Antibiotic prophylaxis probably leads to lower incidence rate of cellulitis compared with no treatment/placebo (moderate certainty).
Antibiotic prophylaxis probably leads to lower time to next episode of cellulitis compared with no treatment/placebo (moderate certainty).
Antibiotic prophylaxis showed no clear difference in hospitalisation compared with no treatment/placebo (low certainty).