Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

966 questions · 1,015 findings · 90 reviews · Headline outcomes only

No studies found 256 · 25.2%GRADE not reported 62 · 6.1%Very low 271 · 26.7%Low 269 · 26.5%Moderate 111 · 10.9%High 46 · 4.5%

Vitamin C vs allopurinol

Joint pain reduction ‐ not reported · participants with chronic gout and sUA level > 0.36mmol/L

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin C vs allopurinol

Participant global assessment · participants with chronic gout and sUA level > 0.36mmol/L

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin C vs allopurinol

Tophus regression · participants with chronic gout and sUA level > 0.36mmol/L

The review found no eligible studies for this question.

1 finding from 1 review

Vitamin C vs allopurinol

Acute gout attacks · participants with chronic gout and sUA level > 0.36mmol/L

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Protein energy wasting (malnutrition) · non‐diabetic adults with CKD

The intervention showed no clear difference in protein energy wasting (malnutrition) (low certainty).

1 finding from 1 review