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Evidence found and GRADE certainty

766 questions · 806 findings · 76 reviews · ENT

No studies found 293 · 36.4%GRADE not reported 6 · 0.7%Very low 244 · 30.3%Low 170 · 21.1%Moderate 85 · 10.5%High 8 · 1%

Intervention not reported

Mean improvement in pure‐tone average hearing threshold across all frequencies Decibels Scale from: 0 to 120 · patients with idiopathic sudden sensorineural hearing loss or tinnitus
1 finding from 1 review

Intervention not reported

More than 50% improvement in pure‐tone average threshold Risk ratio · patients with idiopathic sudden sensorineural hearing loss or tinnitus

The intervention showed no clear difference in more than 50% improvement in pure‐tone average threshold Risk ratio (moderate certainty).

1 finding from 1 review

Intervention not reported

More than 25% improvement in pure‐tone average threshold Risk ratio · patients with idiopathic sudden sensorineural hearing loss or tinnitus

The intervention probably leads to higher more than 25% improvement in pure‐tone average threshold Risk ratio (moderate certainty).

1 finding from 1 review

Intervention not reported

All‐cause study withdrawal Investigator‐recorded · patients with allergic rhinitis1

The intervention showed no clear difference in all‐cause study withdrawal Investigator‐recorded (high certainty).

1 finding from 1 review

Intervention not reported

Change in allergic rhinitis daily symptom score during the grass pollen season Each daily symptom score was the summation of (i) runny nose score, (ii) itchy nose score and (iii) sneezing score (each of these scores self recorded on a severity sca... · patients with allergic rhinitis1
1 finding from 1 review

Intervention not reported

Percentage of well days during the grass pollen season Well days were those days with a symptom score of less than or equal to 2, and no use of rescue medication Scale from: 0 to 100 · patients with allergic rhinitis1
1 finding from 1 review

Intervention not reported

Total quality of life score over 12 weeks Assessed as the total score over the entire 12‐week study period in the Juniper RQLQ, i.e. a patient‐specific test instrument derived from 28 questions drawn from 7 dimensions (sleep, non‐hay fever symptom... · patients with allergic rhinitis1
1 finding from 1 review

Intervention not reported

Percentage of days requiring rescue medication (i.e. as tablets) during the grass pollen season Self recorded each day4 Scale from: 0 to 100 · patients with allergic rhinitis1
1 finding from 1 review

Intervention not reported

Hospitalisation due to any adverse event Investigator‐assessed · patients with allergic rhinitis1

The intervention showed no clear difference in hospitalisation due to any adverse event Investigator‐assessed (moderate certainty).

1 finding from 1 review

Intervention not reported

Any gastrointestinal adverse event Self recorded · patients with allergic rhinitis1

The intervention probably leads to higher any gastrointestinal adverse event Self recorded (moderate certainty).

1 finding from 1 review

Summary of findings: oral steroids plus antibiotic vs control plus antibiotic

Adverse effects [2 weeks to 6 months] · Children with otitis media with effusion

Summary of findings: oral steroids plus antibiotic showed no clear difference in adverse effects [2 weeks to 6 months] compared with control plus antibiotic (low certainty).

1 finding from 1 review