Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

801 questions · 875 findings · 91 reviews

No studies found 182 · 20.8%GRADE not reported 220 · 25.1%Very low 229 · 26.2%Low 128 · 14.6%Moderate 76 · 8.7%High 40 · 4.6%

Guided tissue regeneration (GTR) with barrier membrane (resorbable or non-resorbable) vs Open flap debridement (access flap surgery)

Post-operative adverse events and complications · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
1 finding from 1 review
  • Adverse effects were generally minor. Healing was generally uneventful for both test and control groups. Exposure of the GTR barrier membrane was widely reported, ranging from 20% of sites (non-resorbable…
    16 studies
    GRADE not reported

38% SDF plus oral health education vs oral health instruction plus tonic water

new root-surface carious lesions or restorations · community-dwelling older adults with root caries

SDF had a 62% preventative fraction; no pooled estimate or GRADE rating was reported.

1 finding from 1 review

38% SDF plus potassium iodide and oral health instruction vs oral health instruction plus tonic water

new root-surface carious lesions or restorations · community-dwelling older adults with root caries

SDF plus potassium iodide had a 52% preventative fraction; no pooled estimate or GRADE rating was reported.

1 finding from 1 review