Mean disability (EDSS) score—at 1 week after randomisation · multiple sclerosis patients with acute exacerbations
Corticosteroids or ACTH showed no clear difference in mean disability (EDSS) score—at 1 week after randomisation compared with placebo (moderate certainty).
1 finding from 1 review
Participants with new exacerbations during · multiple sclerosis patients with acute exacerbations
It is very uncertain whether corticosteroids or ACTH changes participants with new exacerbations during compared with placebo (very low certainty).
1 finding from 1 review
Intervention not reported
Total studies: 50 Total participants: 14,926 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
50 participants
GRADE not reported
Intervention not reported
Duloxetine high dose RCTs: 14 Participants: 3683 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
14 participants
Low
Intervention not reported
Duloxetine standard dose RCTs: 18 Participants: 4959 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
18 participants
Moderate
Intervention not reported
Milnacipran high dose RCTs: 2 Participants: 1670 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
2 participants
Low
Intervention not reported
Milnacipran standard dose RCTs: 4 Participants: 1866 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
4 participants
Moderate
Intervention not reported
Duloxetine low dose RCTs: 6 Participants: 1104 · people with chronic pain Interventions: duloxetine low dose (< 60 mg), standard dose (60 mg), and high dose (> 60 mg); milnacipran…
1 finding from 1 review
no estimate extracted
6 participants
Moderate
Cost‐effectiveness · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Number of participants with symptomatic UTI · long‐term bladder management
Single‐use (sterile) catheter showed no clear difference in number with symptomatic UTI1 compared with multiple‐use (clean) catheter (low certainty).
1 finding from 1 review
Participant‐assessed outcome(satisfaction) · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participant‐assessed outcome(preference) · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse effects (urethral trauma/bleeding/haematuria) · long‐term bladder management
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Finding 19: social exclusion. Some parents, predominantly from LMICs, were less accepting of childhood vaccination due to their experiences of social exclusion. Social exclusion may involve economic disadvantage, residential segregation, a lack of... · groups. Numerous parents characterised infants and young children as weak and vulnerable, and in need of protection against multiple…
1 finding from 1 review
no estimate extracted
Studies not reported
Moderate
Intervention not reported
Index test · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
≥ 1 of cough, fever, or poor weight gain · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review
Intervention not reported
≥ 1 of cough, fever, or decreased playfulness · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review
Intervention not reported
≥ 1 of cough, fever, poor weight gain, or tuberculosis close contact (WHO 4‐symptom symptom screen) · children with close tuberculosis contacts Index tests: groups of multiple symptoms Role: an initial test Threshold for index tests: any 1…
1 finding from 1 review
Cumulative live birth · transfer following in vitro fertilisation or intracytoplasmic sperm injection
Repeated single embryo transfer (mixed policies) showed no clear difference in cumulative live birth compared with multiple embryo transfer (low certainty).
1 finding from 1 review
Clinical pregnancy rate · transfer following in vitro fertilisation or intracytoplasmic sperm injection
Repeated single embryo transfer (mixed policies) showed no clear difference in clinical pregnancy rate compared with multiple embryo transfer (low certainty).
1 finding from 1 review