Findings

What do systematic reviews say?

2,261 questions · 2,280 findings · 114 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 856 · 37.5%GRADE not reported 58 · 2.5%Very low 550 · 24.1%Low 502 · 22%Moderate 271 · 11.9%High 43 · 1.9%

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music

QoL · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs self‐selected music

Exercise capacity (change from baseline) · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Adherence to treatment (number of participants undertaking physical activity) · people with CF

It is very uncertain whether the intervention changes adherence to treatment (number of participants undertaking physical… (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
RR 3.67 [1.24, 10.85]
1 study · 34 participants
Very low

Intervention not reported

Frequency of hospitalisation for respiratory infection · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Frequency of non‐hospitalised respiratory infection · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

FEV1 % predicted (change from baseline) · people with CF

It is very uncertain whether the intervention changes FEV1 % predicted (change from baseline) (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Intervention not reported

FVC % predicted (change from baseline) · people with CF

It is very uncertain whether the intervention changes FVC % predicted (change from baseline) (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Intervention not reported

QoL (change from baseline) · people with CF

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Intervention not reported

Exercise capacity (change from baseline) VO2 peak · people with CF

It is very uncertain whether the intervention changes exercise capacity (change from baseline) VO2 peak (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music

Frequency of non‐hospitalised respiratory infection · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music

FEV1 % predicted: absolute change from baseline · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music

FVC (% predicted) Change from baseline · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music

QoL · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ specifically‐composed music vs no music

Exercise capacity (change from baseline) · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music

Adherence · people with CF

It is very uncertain whether motivational interventions to improve adherence to airway clearance… changes adherence to treatment Morisky‐Green questionnaire (number of… compared with no music (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
RR 1.03 [0.57, 1.86]
1 study · 28 participants
Very low

Motivational interventions to improve adherence to airway clearance treatment for people with CF ‐ self‐selected music vs no music

Frequency of hospitalisation for respiratory infection · people with CF

It is very uncertain whether motivational interventions to improve adherence to airway clearance… changes frequency of hospitalisation for respiratory infection compared with no music (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
RR 0.58 [0.18, 1.86]
1 study · 28 participants
Very low

Digital technology (TIM) vs standard treatment (TBM)

Adherence to inhaled therapies cMPR · children aged 5 to 16 years

Digital technology (TIM) may leads to higher adherence to the inhaled treatment: compared with standard treatment (TBM) (low certainty).

1 finding from 1 review

Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
MD 24 [2.95, 45.05]
1 study · 20 participants
Low

Digital technology (web‐based platform CFHealthHub) vs usual care

Pulmonary exacerbations · adults (aged 16 years and over) with CF

Digital technology (web‐based platform CFHealthHub) probably leads to lower number of pulmonary exacerbations compared with usual care (moderate certainty).

1 finding from 1 review

Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
rate ratio 0.92
1 study · 607 participants
Moderate

Digital technology (TIM) vs standard treatment (TBM)

Treatment burden · children aged 5 to 16 years

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Digital technology (TIM) vs standard treatment (TBM)

QoL · children aged 5 to 16 years

The review found no eligible studies for this question.

1 finding from 1 review

Digital technology for monitoring adherence to inhaled therapies in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found