Healing - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy)
It is very uncertain whether cone beam computed tomography (CBCT) preoperative evaluation changes healing - 1 year compared with conventional periapical radiography (very low certainty).
1 finding from 1 review
Sensitivity · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
AI algorithms have high pooled sensitivity (0.85) for detecting dental caries; ungraded, with very high heterogeneity (I2>95%) and evidence of publication bias.
1 finding from 1 review
Specificity · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
AI algorithms have high pooled specificity (0.90) for detecting dental caries; ungraded, with very high heterogeneity (I2>95%).
1 finding from 1 review
Area under the summary ROC curve · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
The area under the summary ROC curve for AI caries detection is 0.86, indicating high overall diagnostic accuracy; ungraded.
1 finding from 1 review
Positive likelihood ratio · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
A positive AI test raises caries probability substantially (LR+ 10.44; positive post-test probability 79%); ungraded.
1 finding from 1 review
Log diagnostic odds ratio · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
AI algorithms show strong pooled discriminative accuracy for dental caries (log DOR 4.37; DOR 70.9); ungraded.
1 finding from 1 review
Negative likelihood ratio · Patients undergoing dental caries detection on dental images (teeth/surfaces across imaging modalities)
A negative AI test lowers caries probability substantially (LR- 0.17; negative post-test probability 6%); ungraded.
1 finding from 1 review
Rescue analgesia · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
Ibuprofen taken pre-emptively (about 1 hour before treatment) showed no clear difference in rescue analgesia compared with ibuprofen taken post-treatment; GRADE not reported.
1 finding from 1 review
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
It is very uncertain whether ibuprofen taken pre-emptively (about 1 hour before treatment) changes pain intensity (VAS 0-100 mm) compared with ibuprofen taken post-treatment (very low certainty).
3 findings from 1 review
MD -9.74 [-47.88, 28.40]
2 studies · 69 participants
Very low
MD -11.30 [-16.27, -6.33]
1 study · 41 participants
Very low
MD -8.43 [-30.37, 13.50]
2 studies · 69 participants
Very low
Time off school or work · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Failure to complete orthodontic treatment due to pain · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Quality of life or participant satisfaction · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Streptococcus mutans load in the oral cavity (saliva and/or dental plaque) · Adults and children (general population)
In a sensitivity analysis assuming a 0.95 baseline-to-endpoint correlation for the sugar-free gum arm, the effect remained significant (SMD -0.55, 95% CI -0.80 to -0.30; 13 trials, I2 73%); certainty not formally graded.
2 findings from 1 review
White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)
Two studies found adhesive flash-free brackets did not clinically reduce enamel demineralization or white spot lesions versus conventional brackets, though they reduced pathogenic bacteria (ungraded).
1 finding from 1 review
MRONJ (incidence proportion) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence proportion) compared with standard care (very low certainty).
1 finding from 1 review
MRONJ (incidence rate: cases per patient-year) · Men with metastatic prostate cancer receiving intravenous zoledronic acid (at risk of MRONJ)
It is very uncertain whether dental examinations at three-month intervals and preventive treatments changes MRONJ (incidence rate: cases per patient-year) compared with standard care (very low certainty).
1 finding from 1 review
Retention of sealant (complete or partial retention) · Pits and fissures of permanent (posterior) teeth
High-viscosity glass-ionomer ART sealants showed 4-year retention of 68% (95% CI 61-75%); evidence ungraded.
6 findings from 1 review
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Caries-free sealed pits and fissures · Pits and fissures of permanent (posterior) teeth
Pits and fissures sealed with high-viscosity glass-ionomer ART sealants remained dentine lesion-free in 100% (95% CI 99-100%) at 1-year; evidence ungraded.
6 findings from 1 review
Show 3 more findings
Dental attendance · primary or secondary school pupils
It is very uncertain whether criteria-based screening (dentist refers using pre-established… changes dental attendance compared with traditional screening (very low certainty).
1 finding from 1 review