Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,092 questions · 3,199 findings · 339 reviews · Headline outcomes only

No studies found 714 · 22.3%GRADE not reported 181 · 5.7%Very low 695 · 21.7%Low 908 · 28.4%Moderate 568 · 17.8%High 133 · 4.2%

Summary of findings: intranasal steroids plus oral antibiotic vs control plus antibiotic

OME resolution at intermediate‐term · Children with otitis media with effusion

Summary of findings: intranasal steroids plus oral antibiotic showed no clear difference in OME resolution at intermediate‐term compared with control plus antibiotic (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs mechanical bowel preparation alone

Surgical site infection · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… probably leads to lower SSI compared with mechanical bowel preparation alone (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

Surgical site infection · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in surgical site infections compared with no bowel preparation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

Anastomotic leakage · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in anastomotic leakage compared with no bowel preparation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

All‐cause mortality · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in mortality compared with no bowel preparation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs no bowel preparation

Postoperative ileus · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in incidence of postoperative ileus compared with no bowel preparation (low certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs mechanical bowel preparation alone

Anastomotic leakage · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… probably leads to lower anastomotic leakage compared with mechanical bowel preparation alone (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs mechanical bowel preparation alone

All‐cause mortality · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in mortality compared with mechanical bowel preparation alone (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Combined mechanical and oral antibiotic bowel preparation vs mechanical bowel preparation alone

Postoperative ileus · Patients undergoing elective colorectal surgery

Summary of findings table ‐ Combined mechanical and oral antibiotic… showed no clear difference in incidence of postoperative ileus compared with mechanical bowel preparation alone (low certainty).

1 finding from 1 review