Total mortality · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in total mortality compared with standard blood pressure targets (moderate certainty).
1 finding from 1 review
Total serious adverse events · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in total serious adverse events compared with standard blood pressure targets (low certainty).
1 finding from 1 review
Cardiovascular events · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in total cardiovascular events compared with standard blood pressure targets (low certainty).
1 finding from 1 review
Cardiovascular mortality · cardiovascular disease with high blood pressure
Lower blood pressure targets showed no clear difference in cardiovascular mortality compared with standard blood pressure targets (moderate certainty).
1 finding from 1 review
Withdrawals due to adverse events · cardiovascular disease with high blood pressure
It is very uncertain whether lower blood pressure targets changes participant withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty).
1 finding from 1 review
Outcomes · patients with cancer with venous thromboembolism
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · patients with cancer with venous thromboembolism
Low molecular weight heparin showed no clear difference in mortality compared with unfractionated heparin (low certainty).
1 finding from 1 review
Recurrent VTE · patients with cancer with venous thromboembolism
Low molecular weight heparin showed no clear difference in recurrent VTE compared with unfractionated heparin (low certainty).
1 finding from 1 review
Major bleeding · patients with cancer with venous thromboembolism
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Minor bleeding ‐ not reported · patients with cancer with venous thromboembolism
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life ‐ not reported · patients with cancer with venous thromboembolism
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Postphlebitic syndrome ‐ not reported · patients with cancer with venous thromboembolism
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Thrombocytopenia · patients with cancer with venous thromboembolism
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Rate of orthodontic tooth movement during space closure stage (maxillary arch), mm/month · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
It is very uncertain whether low level laser therapy (LLLT) changes rate of orthodontic tooth movement during space closure stage… compared with conventional orthodontic appliance treatment (very low certainty).
1 finding from 1 review
Side effects or other adverse events · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
1 finding from 1 review
MMP-9 location/depth · Human carious dentin
Opposite effect directions were reported for MMP-9 by lesion depth or location (very low certainty).
1 finding from 1 review
no estimate extracted
3 studies
Very low
Periodontal health during molar intrusion · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
1 finding from 1 review
Abellan 2021 assessed periodontal health (plaque index, pocket depth, bleeding on probing) after intrusion of maxillary molars; no evidence of significant difference with LLLT. Statistical test results not published.
1 study
GRADE not reported
Total number of orthodontic appliance adjustment appointments during alignment stage · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
It is very uncertain whether low level laser therapy (LLLT) changes total number of orthodontic appliance adjustment appointments during… compared with conventional orthodontic appliance treatment (very low certainty).
1 finding from 1 review
Discomfort/pain · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
It is very uncertain whether low level laser therapy (LLLT) changes patient perception of pain and discomfort (VAS 0 to 100 mm) compared with conventional orthodontic appliance treatment (very low certainty).
1 finding from 1 review
Duration of orthodontic treatment during alignment stage · Adolescents and adults with malocclusion undergoing fixed orthodontic appliance treatment
It is very uncertain whether low level laser therapy (LLLT) changes duration of orthodontic treatment during alignment stage compared with conventional orthodontic appliance treatment (very low certainty).
1 finding from 1 review