Gain of 3 or more lines of visual acuity · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes gain of three or more lines visual acuity ‐ 24 months** compared with sham (very low certainty).
1 finding from 1 review
RR 4.12 [0.48, 34.99]
Studies not reported
Very low
Change in retinal thickness (micron) (negative is better) · macular edema in diabetes
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Cataract progression ‐ 24 months · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg showed no clear difference in cataract progression ‐ 24 months compared with sham (low certainty).
1 finding from 1 review
RR 3 [0.97, 9.3]
Studies not reported
Low
Use of IOP‐lowering medications ‐ 24 months · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes use of IOP‐lowering medications ‐ 24 months compared with sham (very low certainty).
1 finding from 1 review
RR 21.6 [1.32, 354.7]
Studies not reported
Very low
Surgery for glaucoma ‐ 24 months · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Change in visual acuity (logMAR) ‐ 12 months (negative is better) · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in visual acuity (logMAR) ‐ 12 months (negative is better) compared with macular laser (very low certainty).
1 finding from 1 review
MD 0.02
Studies not reported
Very low
Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg showed no clear difference in gain of three or more lines visual acuity ‐ 12 months compared with macular laser (low certainty).
1 finding from 1 review
RR 0.85 [0.55, 1.3]
Studies not reported
Low
Change in retinal thickness (micron) (negative is better) · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in retinal thickness (micron) (negative is better) compared with macular laser (very low certainty).
1 finding from 1 review
MD 5
Studies not reported
Very low
Cataract progression · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg probably leads to higher cataract progression ‐ 9 to 24 months compared with macular laser (moderate certainty).
1 finding from 1 review
RR 2.68 [2.21, 3.24]
Studies not reported
Moderate
Use of IOP‐lowering medications · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg probably leads to higher use of IOP‐lowering medications ‐ 9 to 24 months compared with macular laser (moderate certainty).
1 finding from 1 review
RR 3.92 [2.59, 5.96]
Studies not reported
Moderate
Surgery for glaucoma ‐ 24 months · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg showed no clear difference in surgery for glaucoma ‐ 9 to 24 months compared with macular laser (low certainty).
1 finding from 1 review
RR 11.68 [0.63, 216]
Studies not reported
Low
Change in visual acuity (logMAR) ‐ 12 months (negative is better) · macular edema in diabetes
1 finding from 1 review
Gain of 3 or more lines of visual acuity · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Central retinal thickness μm (CRT) change at 1 year The aim of treatment is to reduce central retinal thickness so thinner is better. · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes change in central retinal thickness (micron) ‐ 12 months (negative… compared with antiVEGF (very low certainty).
1 finding from 1 review
Cataract progression · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Use of IOP‐lowering medications · macular edema in diabetes
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Surgery for glaucoma · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical cure according to criteria established by study authors Mild‐moderate PID · women with PID
Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors… compared with regimens containing cephalosporin (low certainty).
1 finding from 1 review
RR 1.02 [0.95, 1.09]
Studies not reported
Low
Clinical cure according to criteria established by study authors Severe PID · women with PID
Regimens containing clindamycin plus aminoglycoside showed no clear difference in clinical cure according to criteria established by authors Severe PID compared with regimens containing cephalosporin (moderate certainty).
1 finding from 1 review
RR 1 [0.95, 1.06]
Studies not reported
Moderate
Adverse events: any antibiotic‐related adverse event leading to discontinuation of therapy · women with PID
It is very uncertain whether regimens containing clindamycin plus aminoglycoside changes adverse events: any antibiotic‐related adverse event leading to… compared with regimens containing cephalosporin (very low certainty).
1 finding from 1 review
RR 0.78 [0.18, 3.42]
Studies not reported
Very low