Diabetic complications · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
The review found no eligible studies for this question.
1 finding from 1 review
Complications and side effects · People on antiresorptive treatment undergoing tooth extraction (at risk of MRONJ)
1 finding from 1 review
No intraoperative complications occurred in either group. Postoperative complications: 6 participants (15.4%) in the mucoperiosteal flap group and 1 participant (2.6%) in the PRF group.
1 study · 77 participants
GRADE not reported
Pain at 48 hours (VAS 0-10) · Adults (>18 years) with established dry socket following permanent tooth extraction
Topical anaesthetic gel (prilocaine-lidocaine) showed no clear difference in pain at 48 hours (VAS 0-10) compared with eugenol; GRADE not reported.
1 finding from 1 review
Postoperative pain intensity in the immediate postobturation period (up to 72 hours), continuous (VAS) · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
Single-visit root canal treatment showed no clear difference in postoperative pain intensity in the immediate postobturation period… compared with multiple-visit root canal treatment (two or more visits) (low certainty).
1 finding from 1 review
Adverse effects of treatment · People with diabetes mellitus (type 1 or type 2, mostly type 2) and periodontitis, at least 16 years of age
1 finding from 1 review
Dental caries prevalence · School children (aged 4 to 15 years), primary and secondary schools in the UK and India
1 finding from 1 review
Milsom 2006 measured prevalence of dental caries as mean number of teeth with active caries in primary teeth (dt) and permanent teeth (DT); post-intervention changes from baseline were not significant, and the authors…
1 study · 16684 participants
GRADE not reported
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel (0.2%, intrasocket) showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.12%) (low certainty).
1 finding from 1 review
Healing of MRONJ (remission) · People with established (manifest) MRONJ
It is very uncertain whether teriparatide 56.5 microg weekly in addition to standard care changes healing of MRONJ (remission) compared with teriparatide 20 microg daily in addition to standard care (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Tap water irrigation (monoject syringe) led to lower presence of dry socket compared with no rinsing; GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel 1% showed no clear difference in presence of dry socket compared with chlorhexidine gel 0.2%; GRADE not reported.
1 finding from 1 review
Retention of sealant (complete or partial retention) · Children who were regular dental attenders with caries-free first or second primary molars (public health service clinic, Brazil)
1 finding from 1 review
Effect estimate not calculable. All sealants were completely or partially retained; 40 (1 RCT). Flowable composite: 39/40 completely retained (1 partially lost) at 6 months; resin-based: 33 completely and 7 partially…
1 study · 40 participants
Low
Number of caries in permanent teeth (DT index) · School children, primary school in Saudi Arabia
It is very uncertain whether referral to a specific dental treatment facility changes number of caries in permanent teeth (DT index) compared with generic advice letter to see a dentist (very low certainty).
1 finding from 1 review
MRONJ after tooth extraction (incidence proportion) · People on antiresorptive treatment undergoing tooth extraction (at risk of MRONJ)
Subperiosteal prepared (SPP) wound closure after tooth extraction showed no clear difference in MRONJ after tooth extraction (incidence proportion) compared with epiperiosteal prepared (EPP) wound closure after tooth extraction (low certainty).
1 finding from 1 review
Attachment change · Adults with a clinical diagnosis of (chronic) periodontitis (1999 classification); studies of aggressive periodontitis, systemic disorders…
Full-mouth disinfection (FMD): scaling/root planing (subgingival… showed no clear difference in change in clinical attachment level (CAL) compared with quadrant scaling and root planing (control): SRP of each quadrant in… (low certainty).
1 finding from 1 review
Serum high-sensitivity C-reactive protein (hs-CRP) · Patients with cardiovascular disease and chronic periodontitis
1 finding from 1 review
Serum hs-CRP tested at one year; as loss to follow-up was almost 90%, data not considered useful for analysis (no usable estimate).
1 study · 37 participants
GRADE not reported
Cost implications of antibiotic provision · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
The review found no eligible studies for this question.
1 finding from 1 review
Pain at 1 month · People aged 10 years or above requiring root canal treatment; permanent teeth with completely formed apex and without internal resorption
1 finding from 1 review
One study (Dhyani 2022) reported pain at 1 month: 60 teeth (all vital at enrolment, mechanical NiTi), 0 events (no participant reported pain at 1 month); no meta-analysis
1 study · 60 participants
GRADE not reported
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Honey (Manuka, topical) showed no clear difference in presence of dry socket compared with chlorhexidine rinse (0.2%); GRADE not reported.
1 finding from 1 review
Presence of dry socket · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)
Chlorhexidine gel (0.2%, intrasocket) probably leads to lower presence of dry socket compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Costs · People undergoing aerosol-generating procedures (AGPs) in a dental setting
The review found no eligible studies for this question.
1 finding from 1 review