Intervention not reported
The proportion of patients who discontinued study drug because of adverse events excluding relapses at two years · Patients with relapsing‐remitting multiple sclerosis
The intervention probably leads to higher the proportion of patients who discontinued study drug because of… (moderate certainty).
1 finding from 1 review
Intervention not reported
The proportion of patients with lymphopenia at two years · Patients with relapsing‐remitting multiple sclerosis
The intervention probably leads to higher the proportion of patients with lymphopenia at two years (moderate certainty).
1 finding from 1 review
Adverse effects (any)* · women during pregnancy
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Low birthweight · women during pregnancy
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Preterm birth · women during pregnancy
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Maternal anaemia at term or near term (haemoglobin (Hb) less than 110 g/L at 34 weeks' gestation or more) · women during pregnancy
1 finding from 1 review
no estimate extracted
470 participants
Very low
Maternal iron deficiency at term or near term (as defined by authors of the trials, based on any indicator of iron status at 34 weeks' gestation or more) · women during pregnancy
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Maternal death · women during pregnancy
1 finding from 1 review
no estimate extracted
0 participants
GRADE not reported
Attention · people with multiple sclerosis
Cognitive training showed no clear difference in attention compared with any control (low certainty).
1 finding from 1 review
Immediate verbal memory · people with multiple sclerosis
It is very uncertain whether cognitive training combined with other neuropsychological… changes immediate verbal memory compared with any control (very low certainty).
1 finding from 1 review
Delayed memory · people with multiple sclerosis
Cognitive training combined with other neuropsychological… probably leads to higher delayed memory compared with any control (moderate certainty).
1 finding from 1 review
Everyday cognitive performance / patient's report · people with multiple sclerosis
Cognitive training combined with other neuropsychological… showed no clear difference in everyday cognitive performance/patient's report compared with any control (low certainty).
1 finding from 1 review
Depression · people with multiple sclerosis
Cognitive training combined with other neuropsychological… showed no clear difference in depression compared with any control (low certainty).
1 finding from 1 review
Fatigue · people with multiple sclerosis
It is very uncertain whether cognitive training combined with other neuropsychological… changes fatigue compared with any control (very low certainty).
1 finding from 1 review
Information processing speed · people with multiple sclerosis
It is very uncertain whether cognitive training changes information processing speed compared with any control (very low certainty).
1 finding from 1 review
Memory span · people with multiple sclerosis
Cognitive training may leads to higher memory span compared with any control (low certainty).
1 finding from 1 review
Cognitive subdomain: working memory measured at the end of · people with multiple sclerosis
It is very uncertain whether cognitive training changes working memory compared with any control (very low certainty).
1 finding from 1 review
Immediate verbal memory · people with multiple sclerosis
Cognitive training showed no clear difference in immediate verbal memory compared with any control (low certainty).
1 finding from 1 review
Executive function (specific cognitive function) · people with multiple sclerosis
It is very uncertain whether cognitive training changes executive functions compared with any control (very low certainty).
1 finding from 1 review
Depression · people with multiple sclerosis
It is very uncertain whether cognitive training changes depression compared with any control (very low certainty).
1 finding from 1 review