Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,266 questions · 1,314 findings · 160 reviews · Headline outcomes only

No studies found 309 · 23.5%GRADE not reported 34 · 2.6%Very low 356 · 27.1%Low 393 · 29.9%Moderate 187 · 14.2%High 35 · 2.7%

Warm compresses vs control (hands off or no warm compress)

Intact perineum · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

Warm compresses showed no clear difference in intact perineum compared with control (hands off or no warm compress) (moderate certainty).

1 finding from 1 review

Warm compresses vs control (hands off or no warm compress)

Perineal trauma requiring suturing · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

It is very uncertain whether warm compresses changes perineal trauma requiring suturing compared with control (hands off or no warm compress) (very low certainty).

1 finding from 1 review

Warm compresses vs control (hands off or no warm compress)

1st degree tear · pregnant women expecting a vaginal birth, singleton vertex presentation at term, with no medical complications

It is very uncertain whether warm compresses changes 1st degree tear compared with control (hands off or no warm compress) (very low certainty).

1 finding from 1 review

LOD vs medical interventions

Improvement in androgenic symptoms · Women with symptoms of PCOS

LOD showed no clear difference in improvement in androgenic symptoms at 6 months (hirsutism/acne) ‐… compared with medical interventions (low certainty).

2 findings from 1 review

LOD vs medical interventions

Harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of participants: 332 (2 RCTs) Harms: OHSS rates at 6 months ‐ LOD vs gonadotrophins N of participants: 33 (1 RCT) · Women with symptoms of PCOS

LOD probably leads to lower harms: GI Upset at 6 months ‐ LOD vs metformin + clomiphene N of… compared with medical interventions (moderate certainty).

1 finding from 1 review

Intervention not reported

Outcomes1 · patients undergoing epilepsy surgery with medically refractory epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Responder Rate · patients undergoing epilepsy surgery with medically refractory epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

ILAE Epilepsy Surgery Outcome · patients undergoing epilepsy surgery with medically refractory epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Quality of Life · patients undergoing epilepsy surgery with medically refractory epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Back School vs medical care

Disability (intermediate‐term) RMDQ. Scale from: 0 to 24. · people with low back pain

It is very uncertain whether back School changes disability: intermediate‐term compared with medical care (very low certainty).

1 finding from 1 review