Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,736 questions · 15,265 findings · 1,163 reviews · Headline outcomes only

No studies found 3,871 · 25.4%GRADE not reported 810 · 5.3%Very low 4,242 · 27.8%Low 3,879 · 25.4%Moderate 1,999 · 13.1%High 464 · 3%

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Lay health worker‐led psychological interventions vs usual care

Prevalence of PTSD · adults with post‐traumatic stress and CMDs

It is very uncertain whether lay health worker‐led psychological interventions changes prevalence of PTSD ‐ intermediate term (1 to 6 months) Diagnosis… compared with usual care (very low certainty).

1 finding from 1 review

Lay health worker‐led psychological interventions vs usual care

Adverse events RR < 1 indicates lower risk of adverse events · adults with common mental disorders

Lay health worker‐led psychological interventions may leads to lower adverse events RR < 1 indicates lower risk of adverse events compared with usual care (low certainty).

1 finding from 1 review

Lifestyle interventions vs placebo or usual care

Overall survival (24 months) · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes overall survival (24 months) compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Lifestyle interventions vs placebo or usual care

Adverse events – musculoskeletal · weight reduction in obesity to improve survival in women with endometrial cancer

It is very uncertain whether summary of findings table ‐ Lifestyle intervention changes adverse events – musculoskeletal compared with usual care compared to placebo (very low certainty).

1 finding from 1 review

Lifestyle interventions vs placebo or usual care

Cardiovascular and metabolic event frequency (12 months) (Number of strokes, myocardial infarctions and hospitalisations for heart failure) · weight reduction in obesity to improve survival in women with endometrial cancer

Summary of findings table ‐ Lifestyle intervention showed no clear difference in cardiovascular and metabolic event frequency (6 months) compared with usual care compared to placebo (low certainty).

1 finding from 1 review

Home‐based record combined with other interventions vs usual care

Proportion of children who received DTP3 or Penta 3 ‐ HBRf only · children aged 1 year

Home‐based record combined with other interventions may leads to higher proportion of children who received DTP3 or Penta 3 ‐ HBRf only compared with routine care (low certainty).

1 finding from 1 review

Home‐based record combined with other interventions vs usual care

Proportion of children who received DTP3 or Penta 3 ‐ HBR + health educationg · children aged 1 year

Home‐based record combined with other interventions may leads to higher proportion of children who received DTP3 or Penta 3 ‐ HBR + health… compared with routine care (low certainty).

1 finding from 1 review

Home‐based record combined with other interventions vs usual care

Proportion of children who received DTP3 or Penta 3 ‐ HBR + stickerh · children aged 1 year

Home‐based record combined with other interventions may leads to higher proportion of children who received DTP3 or Penta 3 ‐ HBR + stickerh compared with routine care (low certainty).

1 finding from 1 review