Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,438 questions · 1,463 findings · 125 reviews · Anaesthesia

No studies found 197 · 13.5%GRADE not reported 203 · 13.9%Very low 307 · 21%Low 441 · 30.1%Moderate 245 · 16.7%High 70 · 4.8%

Beta‐blockers vs control—non‐cardiac surgery

Bradycardia—non‐cardiac surgery ECG · patients with conditions requiring non‐cardiac surgery

Beta‐blocker probably leads to higher bradycardia—non‐cardiac surgery ECG compared with control—non‐cardiac surgery (moderate certainty).

1 finding from 1 review

Beta‐blockers vs control—cardiac surgery

Acute myocardial infarction—cardiac surgery · patients with coronary heart disease and/or valvular heart disease

Beta‐blocker showed no clear difference in acute myocardial infarction—cardiac surgery compared with control—cardiac surgery (moderate certainty).

1 finding from 1 review

Beta‐blockers vs control—cardiac surgery

Ventricular arrhythmias—cardiac surgery ECG · patients with coronary heart disease and/or valvular heart disease

Beta‐blocker probably leads to lower ventricular arrhythmias—cardiac surgery ECG compared with control—cardiac surgery (moderate certainty).

1 finding from 1 review

Beta‐blockers vs control—cardiac surgery

All supraventricular arrhythmias—cardiac surgery ECG · patients with coronary heart disease and/or valvular heart disease

Beta‐blocker leads to lower all supraventricular arrhythmias—cardiac surgery ECG compared with control—cardiac surgery (high certainty).

1 finding from 1 review

Beta‐blockers vs control—non‐cardiac surgery

All‐cause mortality (30 days)—non‐cardiac surgery · patients with conditions requiring non‐cardiac surgery

Beta‐blocker showed no clear difference in all‐cause mortality (30 days)—non‐cardiac surgery compared with control—non‐cardiac surgery (low certainty).

1 finding from 1 review

Beta‐blockers vs control—non‐cardiac surgery

Acute myocardial infarction—non‐cardiac surgery · patients with conditions requiring non‐cardiac surgery

Beta‐blocker leads to lower acute myocardial infarction—non‐cardiac surgery compared with control—non‐cardiac surgery (high certainty).

1 finding from 1 review

Thoracic epidural anaesthesia vs conventional pain control

Persistent pain 3 to 18 months after thoracotomy (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between 3 to 18 m... · Patients undergoing thoracotomy

Thoracic epidural anaesthesia probably leads to lower persistent pain 3 to 18 months after thoracotomy (We defined… compared with conventional pain control (moderate certainty).

1 finding from 1 review

Regional anaesthesia vs conventional pain control

Persistent pain 3 to 12 months after breast cancer surgery (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between... · women with breast cancer undergoing elective surgery

Regional anaesthesia may leads to lower persistent pain 3 to 12 months after breast cancer surgery (We… compared with conventional pain control (low certainty).

1 finding from 1 review

Intervention not reported

Persistent pain 3 to 8 months after caesarean section (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between 3 to... · women after caesarean section

The intervention probably leads to lower persistent pain 3 to 8 months after caesarean section (We defined… (moderate certainty).

1 finding from 1 review

Intervention not reported

Persistent pain 3 to 55 months after iliac crest bone graft harvesting (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient inter... · people after iliac crest bone graft harvesting

The intervention showed no clear difference in persistent pain 3 to 55 months after iliac crest bone graft… (low certainty).

1 finding from 1 review

Intervention not reported

Persistent pain 3 to 6 months after breast cancer surgery (We defined persistent postsurgical pain as new pain that did not exist before the operation, measured using differences in scores based on validated pain scales; patient interview between ... · women with breast cancer undergoing elective surgery

The intervention probably leads to lower persistent pain 3 to 6 months after breast cancer surgery (We… (moderate certainty).

1 finding from 1 review