Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,808 questions · 8,953 findings · 827 reviews · Headline outcomes only

No studies found 1,891 · 21.1%GRADE not reported 380 · 4.2%Very low 2,100 · 23.5%Low 2,449 · 27.4%Moderate 1,684 · 18.8%High 449 · 5%

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Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

Overall survival for subgroup age 60 years and older glioblastoma · high‐grade glioma

Hypofractionated radiotherapy showed no clear difference in overall survival for subgroup aged ≥ 60 years glioblastoma compared with daily conventionally fractionated radiotherapy (high certainty).

1 finding from 1 review

Specific psychological therapy vs alternative specific psychological therapy

Clinical improvement: weight restoration to within the normal weight range for participant sample · people with severe and enduring anorexia nervosa

It is very uncertain whether specific psychological therapy changes clinical improvement: weight restoration to within the normal weight… compared with alternative specific psychological therapy (very low certainty).

1 finding from 1 review

Specific psychological therapy vs alternative specific psychological therapy

Treatment non‐completion: proportion of participants who did not complete treatment · people with severe and enduring anorexia nervosa

It is very uncertain whether specific psychological therapy changes treatment non‐completion: proportion of participants who did not… compared with alternative specific psychological therapy (very low certainty).

1 finding from 1 review

PACK‐CXL with standard therapy vs Standard therapy alone (radiotherapy or chemoradiotherapy)

Proportion of participants with reduction in intraocular inflammation at 4 to 8 weeks Assessed by corneal keratic precipitates, anterior chamber cellular reaction, or other appropriate measure · participants of any age with confirmed cases of bacterial keratitis
1 finding from 1 review