Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,783 questions · 10,022 findings · 882 reviews

No studies found 2,100 · 21%GRADE not reported 1,013 · 10.1%Very low 2,237 · 22.3%Low 2,514 · 25.1%Moderate 1,709 · 17.1%High 449 · 4.5%

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Hypofractionated radiotherapy vs daily conventionally fractionated radiotherapy

Overall survival for subgroup age 60 years and older glioblastoma · high‐grade glioma

Hypofractionated radiotherapy showed no clear difference in overall survival for subgroup aged ≥ 60 years glioblastoma compared with daily conventionally fractionated radiotherapy (high certainty).

1 finding from 1 review

Specific psychological therapy vs alternative specific psychological therapy

Clinical improvement: weight restoration to within the normal weight range for participant sample · people with severe and enduring anorexia nervosa

It is very uncertain whether specific psychological therapy changes clinical improvement: weight restoration to within the normal weight… compared with alternative specific psychological therapy (very low certainty).

1 finding from 1 review

Specific psychological therapy vs alternative specific psychological therapy

Treatment non‐completion: proportion of participants who did not complete treatment · people with severe and enduring anorexia nervosa

It is very uncertain whether specific psychological therapy changes treatment non‐completion: proportion of participants who did not… compared with alternative specific psychological therapy (very low certainty).

1 finding from 1 review