Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,640 questions · 2,709 findings · 446 reviews

No studies found 593 · 21.9%GRADE not reported 241 · 8.9%Very low 538 · 19.9%Low 706 · 26.1%Moderate 516 · 19%High 115 · 4.2%

Corticosteroids vs placebo or usual care

Number of participants with adverse events ‐ superinfection (up to longest · children and adults with sepsis

Corticosteroids showed no clear difference in number of participants with adverse events ‐ superinfection (up to… compared with placebo or usual care (moderate certainty).

1 finding from 1 review

Intervention not reported

Smoking abstinence at longest · People who smoke or who have recently quit

The intervention showed no clear difference in smoking abstinence at longest (low certainty).

1 finding from 1 review

Intervention not reported

Relapse prevention at longest · People who smoke or who have recently quit

It is very uncertain whether the intervention changes relapse prevention at longest (very low certainty).

1 finding from 1 review