Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

864 questions · 895 findings · 140 reviews · Headline outcomes only

No studies found 202 · 22.6%GRADE not reported 53 · 5.9%Very low 227 · 25.4%Low 254 · 28.4%Moderate 131 · 14.6%High 28 · 3.1%

Prophylactic CPAP vs mechanical ventilation

Combined outcome of death and bronchopulmonary dysplasia defined as death at any time and oxygen dependency at 36 weeks' postmenstrual age · preterm infants

Prophylactic CPAP probably leads to lower combined outcome of death and bronchopulmonary dysplasia defined as… compared with mechanical ventilation (moderate certainty).

1 finding from 1 review

Prophylactic CPAP vs mechanical ventilation

Failed treatment defined as the need for mechanical ventilation · preterm infants

Prophylactic CPAP probably leads to lower failed treatment defined as the need for mechanical ventilation compared with mechanical ventilation (moderate certainty).

1 finding from 1 review

Prophylactic or very early CPAP vs supportive care

Bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency at 36 weeks postmenstrual age · preterm infants

Prophylactic or very early CPAP showed no clear difference in bronchopulmonary dysplasia at 36 weeks defined as oxygen dependency… compared with supportive care (moderate certainty).

1 finding from 1 review

Prophylactic or very early CPAP vs supportive care

Death or oxygen requirement at 36 weeks' postmenstrual age · preterm infants

Prophylactic or very early CPAP showed no clear difference in combined outcome of death and bronchopulmonary dysplasia defined as… compared with supportive care (low certainty).

1 finding from 1 review