Adverse effects (e.g. thermal sensitivity, over-eruption, TMJ symptoms, poor aesthetics, reduced oral hygiene) · Adults with chronic periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
One type of occlusal intervention as an adjunct to periodontal therapy vs A different type of occlusal intervention as an adjunct to periodontal therapy (head-to-head)
Outcome not reported · Adults (aged 18 years or older) with a clinical diagnosis of (chronic) periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Occlusal intervention as an adjunct to periodontal therapy vs Sham (placebo) occlusal intervention as an adjunct to periodontal therapy
Outcome not reported · Adults (aged 18 years or older) with a clinical diagnosis of (chronic) periodontitis
The review found no eligible studies for this question.
1 finding from 1 review
Change in probing pocket depth (PPD) · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to surgical periodontal therapy showed no clear difference in probing (pocket) depth change (difference in mean reduction, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review
Attachment change · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to non-surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review
Sites failing to gain 2 mm attachment (proportion) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to lower sites failing to gain 2 mm attachment (proportion) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
RR 0.54 [0.31, 0.96]
6 studies
GRADE not reported
Aesthetics · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
The review found no eligible studies for this question.
1 finding from 1 review
Change in gingival recession (REC) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher change in gingival recession compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 0.26 [0.08, 0.43]
9 studies
GRADE not reported
Treatment / surgical procedure time · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… showed no clear difference in treatment / surgical procedure time compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 23.9
1 study
GRADE not reported
Attachment change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher change in clinical attachment level (attachment gain) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.22 [0.80, 1.64]
16 studies
GRADE not reported
Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.39 [1.08, 1.71]
3 studies
GRADE not reported
Cost/benefit (treatment time plus estimated material costs) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
The review found no eligible studies for this question.
1 finding from 1 review
Hard tissue probing at surgical re-entry (bone gain) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher hard tissue probing at surgical re-entry (bone gain) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 3.37 [3.14, 3.61]
1 study
GRADE not reported
Radiographic bone change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
1 finding from 1 review
Tooth loss · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
1 finding from 1 review
Attachment change · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher change in clinical attachment level (attachment gain) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.25 [0.89, 1.61]
2 studies
GRADE not reported
Change in probing pocket depth (PPD) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) with barrier membrane (resorbable… led to higher change in probing depth (probing depth reduction) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.21 [0.53, 1.88]
11 studies
GRADE not reported
Disease recurrence (% sites with >=2 mm loss of probing attachment from 12 months after treatment) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
The review found no eligible studies for this question.
1 finding from 1 review
Ease of maintenance (% of sites with <4 mm probing depth) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
The review found no eligible studies for this question.
1 finding from 1 review
Change in probing pocket depth (PPD) · Patients with chronic periodontitis (aged 21 years or older) with periodontal infra-bony defects; furcation-involved teeth and aggressive…
Guided tissue regeneration (GTR) combined with bone substitutes/graft led to higher change in probing depth (probing depth reduction) compared with open flap debridement (access flap surgery); GRADE not reported.
1 finding from 1 review
MD 1.24 [0.89, 1.59]
2 studies
GRADE not reported