Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,171 questions · 1,373 findings · 60 reviews · Dental caries

No studies found 282 · 20.5%GRADE not reported 606 · 44.1%Very low 257 · 18.7%Low 160 · 11.7%Moderate 66 · 4.8%High 2 · 0.1%

Vitapex (calcium hydroxide/iodoform) vs 3Mix (ciprofloxacin + metronidazole + minocycline)

Clinical failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) showed no clear difference in clinical failure compared with 3Mix (ciprofloxacin + metronidazole + minocycline); GRADE not reported.

1 finding from 1 review

Vitapex (calcium hydroxide/iodoform) vs ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Vitapex (calcium hydroxide/iodoform) led to higher radiological failure compared with ZOE + calcium hydroxide + iodoform (MPRCF, unnamed product); GRADE not reported.

1 finding from 1 review

Ferric sulphate (FS) + mineral trioxide aggregate (MTA) vs Ferric sulphate (FS)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    mean 22 months
    Assessed pain, soft tissue, mobility, adjacent tissue inflammation, radiolucency, root resorption, pulp canal obliteration (Doyle 2010); no clinical/radiological failure outcome; no significant differences
    1 study · 135 participants
    GRADE not reported

Formocresol (FC) pulpotomy vs Calcium hydroxide pulpectomy

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Self-etch adhesive + acetone-based total-etch adhesive vs Acetone-based total-etch adhesive

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

It is very uncertain whether self-etch adhesive + acetone-based total-etch adhesive changes radiological failure compared with acetone-based total-etch adhesive (very low certainty).

1 finding from 1 review