Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,718 questions · 1,762 findings · 100 reviews · Headline outcomes only

No studies found 507 · 28.8%GRADE not reported 115 · 6.5%Very low 556 · 31.6%Low 444 · 25.2%Moderate 114 · 6.5%High 26 · 1.5%

Summary of findings table ‐ Remifentanil vs diazepam

Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).

1 finding from 1 review

Summary of findings table ‐ Remifentanil vs diazepam

Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

1 finding from 1 review

Mood stabilisers vs placebo

Self‐harm Measured by: clinicians Timing of outcome assessment: end of treatment · patients with borderline personality disorder

It is very uncertain whether mood stabilisers changes self‐harm Timing of outcome assessment: end of treatment (52 weeks… compared with placebo (very low certainty).

1 finding from 1 review