Findings

What do systematic reviews say?

1,938 questions · 2,020 findings · 107 reviews

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No studies found 570 · 28.2%GRADE not reported 266 · 13.2%Very low 578 · 28.6%Low 462 · 22.9%Moderate 118 · 5.8%High 26 · 1.3%

Opioid antagonists vs mood stabilisers

Gambling symptom severity ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs placebo

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 90 participants
Low

Opioid antagonists vs mood stabilisers

Gambling expenditure ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs mood stabilisers

Gambling frequency ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs mood stabilisers

Time spent gambling ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs mood stabilisers

Depressive symptoms · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Opioid antagonists vs mood stabilisers

Anxiety · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 24 participants
Very low

Opioid antagonists vs mood stabilisers

Functional impairment ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Opioid antagonists vs mood stabilisers

Responder status ‐ not measured · treatment of disordered and problem gambling

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs placebo

Anxiety · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Very low

Antidepressants vs placebo

Functional impairment · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 110 participants
Low

Antidepressants vs placebo

Responder status · treatment of disordered and problem gambling

It is very uncertain whether antidepressants changes responder status compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
RR 1.24 [0.93, 1.66]
6 studies · 268 participants
Very low

Opioid antagonists vs placebo

Gambling symptom severity · treatment of disordered and problem gambling

1 finding from 1 review

Pharmacological interventions for the treatment of disordered and problem gambling 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 259 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Fetal immobilisation score at 40 minutes (Degree of fetal immobilisation as defined by trial authors) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Fetal movements ‐ gross body and limb (Degree of fetal immobilisation as defined by trial authors) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Surgical assessment/satisfaction score = 1 or 2 (Technically successful procedure as defined by trial authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to higher surgical assessment/satisfaction score = 1 or 2 (Technically… compared with diazepam (low certainty).

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
RR 2.88 [1.6, 5.15]
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Maternal respiratory rate (Maternal respiratory depression as defined by trial authors or measured using intraoperative maternal arterial oxygen saturation and maternal respiratory rate) · health problem or population

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Maternal OAA score (observer assessment of alertness/sedation) < 4 (Maternal sedation measured using sedation scores as defined by authors) · health problem or population

Summary of findings table ‐ Remifentanil may leads to lower maternal OAA score (observer assessment of alertness/sedation) < 4… compared with diazepam (low certainty).

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
RR 0.09 [0.01, 0.65]
1 study · 50 participants
Low

Summary of findings table ‐ Remifentanil vs diazepam

Perinatal mortality · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Remifentanil vs diazepam

Time taken to perform procedure · health problem or population

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative pharmacological interventions for fetal immobilisation during fetal surgery and invasive procedures 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found