Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,935 questions · 1,986 findings · 260 reviews · Headline outcomes only

No studies found 503 · 25.3%GRADE not reported 76 · 3.8%Very low 593 · 29.9%Low 509 · 25.6%Moderate 241 · 12.1%High 64 · 3.2%

Intermittent iron supplementation (alone or with any other micronutrients) vs no supplementation or placebo

All‐cause morbidity · adolescent and adult menstruating women

Intermittent iron supplementation (alone or with any other… showed no clear difference in all‐cause morbidity (the most frequent event associated with the… compared with no supplementation or placebo (low certainty).

1 finding from 1 review

Intraperitoneal drain vs no intraperitoneal drain

Incidence of STP at 24 hours post‐operatively · women undergoing a diagnostic or operative laparoscopic gynaecological procedure

Intraperitoneal drain may leads to lower incidence of STP at 24 hours post‐operatively compared with no intraperitoneal drain (low certainty).

1 finding from 1 review

Alternative mouse alone vs conventional mouse alone

Incidence of upper body disorders (neck, shoulder, and upper extremity) Questionnaire followed by medical examination · office workers

Alternative mouse alone showed no clear difference in incidence of upper body disorder (neck, shoulder and upper… compared with conventional mouse alone (moderate certainty).

1 finding from 1 review

Alternative mouse alone vs conventional mouse alone

Incidence of neck/shoulder disorder Questionnaire followed by medical examination · office workers

Alternative mouse alone showed no clear difference in incidence of neck or shoulderdisorder Questionnaire followed by… compared with conventional mouse alone (low certainty).

1 finding from 1 review

Alternative mouse alone vs conventional mouse alone

Incidence of right upper extremity disorder Questionnaire followed by medical examination · office workers

Alternative mouse alone showed no clear difference in incidence of right upper extremity disorder Questionnaire followed… compared with conventional mouse alone (moderate certainty).

1 finding from 1 review

Intervention not reported

Mitoxantrone (Direct evidence; 1 RCT; 51 participants) · Patients with RRMS Interventions: Azathioprine, daclizumab, fingolimod, glatiramer acetate, Immunoglobulins, interferon beta 1a ‐1b,…

The intervention may leads to lower mitoxantrone (Direct evidence; 1 RCT; 51 participants) (low certainty).

1 finding from 1 review