What do systematic reviews say?

Autofluorescence-guided bone surgery vs Conventional bone surgery

It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ compared with conventional bone surgery (very low certainty).

• Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes

  1 year
  RR 1.08 [0.85, 1.37]
  1 study · 30 participants
  Very low

Autofluorescence-guided bone surgery vs Tetracycline fluorescence-guided bone surgery

It is very uncertain whether autofluorescence-guided bone surgery changes healing of MRONJ (mucosal integrity) compared with tetracycline fluorescence-guided bone surgery (very low certainty).

• Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes

  1 year
  RR 1.05 [0.86, 1.30]
  1 study · 34 participants
  Very low

Platelet-rich fibrin after bone surgery vs Bone surgery alone

It is very uncertain whether platelet-rich fibrin after bone surgery changes healing of MRONJ (mucosal integrity and absence of infection) compared with bone surgery alone (very low certainty).

• Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes

  1 year
  RR 1.05 [0.90, 1.22]
  1 study · 47 participants
  Very low

Sulphinpyrazone vs placebo

The review found no eligible studies for this question.

• Medical adjuvant treatment to increase patency of arteriovenous fistulae and grafts 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Silicone‐filled vs saline‐filled implants

It is very uncertain whether silicone‐filled changes reintervention Number of women with reintervention compared with saline‐filled implants (very low certainty).

• Different types of implants for reconstructive breast surgery 2016 · Cochrane Headline outcomes only
  OR 0.08 [0.01, 0.43]
  1 study · 60 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  17 studies · 1381 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 1021 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 221 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 53 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 632 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 498 participants
  Low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 573 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 79 participants
  Very low

Music intervention plus standard care vs usual care

• Music interventions for improving psychological and physical outcomes in people with cancer 2021 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Inlay autogenous bone graft (iliac crest) vs Autogenous onlay bone graft (iliac crest)

Autogenous inlay bone graft (iliac crest) showed no clear difference in graft failure compared with autogenous onlay bone graft (iliac crest); GRADE not reported.

• Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant… 2009 · Cochrane All outcomes

  Up to 1 year post-loading
  OR 1.33 [0.07, 24.32]
  1 study · 23 participants
  GRADE not reported